Digital Simulator for Entrepreneurial Finance (FINANCEn_LAB)
Otro Materias > Ciencias Sociales Universidad Europea del Atlántico > Investigación > Proyectos I+D+I Cerrado Inglés The main proposal of this project is to create digital interactive tools that will help the end-beneficiaries (potential and current entrepreneurs) to develop skills and acquire necessary practical knowledge to effectively apply for funding and manage their financial situation. From the general perspective, our project is expected to contribute to the improvement in financial literacy, especially, among HE students, as potential entrepreneurs, through an effective method of learning by doing. The project aims at covering the gap of practical financial competences considered as a critical barrier for entrepreneurship. Possible solution goes through cooperation between financing actors and educational sector. Thus, common training will be complemented with real practice, which includes individual and collaborative work, very different from traditional school assignments, since it will connect funding agents (banking professionals, investors, mentors and similar) with entrepreneurs and students. This DIGITAL LEARNING ENVIRONMENT BASED ON COLLABORATIVE LEARNING with financial agents is the core of our innovative proposal. Besides that, the project will deploy actions to empower HE teachers and entrepreneur coaches. Thus, the project will reach the following segments of people: university students, entrepreneurs, teachers, start-up incubators, financial agents for an estimated total of 840 direct participants and 14600 additional reached online. The main project activities will be oriented to the production of four intellectual outputs: 1) Practical cases in entrepreneurial finance for training purposes. 2) Digital Simulator for entrepreneurial finance (trainer’s tool). 3) Digital Simulator for entrepreneurial finance (self-learning tool). 4) Report on recommendations for entrepreneurial finance stakeholders and policy makers. The project implies cooperation of different type of organizations. The HE institutions and Banking/Financial sector will collaborate closely to ensure that we use appropriate content. Representative institutions will incorporate the tools into their trainings and will disseminate the project results properly. Entrepreneurial institutions will support the outputs creation attracting the attention of practitioners and professionals in the entrepreneurial field. The project pursues long term impact by providing HE lecturers, VET/adult training providers and Entrepreneurial institutions with innovative tools in order to spread the practical knowledge on entrepreneurial funding. It is of special interest to raise awareness on the different alternative sources of funding besides the traditional bank loans, such as crowdfunding, business angels, capital venture and so on, and offer current and future entrepreneurs practical training since it will also generate significant impact measured over time. metadata , FUNIBER mail SIN ESPECIFICAR (2020) Digital Simulator for Entrepreneurial Finance (FINANCEn_LAB). Repositorio de la Universidad. (Inédito)
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The main proposal of this project is to create digital interactive tools that will help the end-beneficiaries (potential and current entrepreneurs) to develop skills and acquire necessary practical knowledge to effectively apply for funding and manage their financial situation. From the general perspective, our project is expected to contribute to the improvement in financial literacy, especially, among HE students, as potential entrepreneurs, through an effective method of learning by doing. The project aims at covering the gap of practical financial competences considered as a critical barrier for entrepreneurship. Possible solution goes through cooperation between financing actors and educational sector. Thus, common training will be complemented with real practice, which includes individual and collaborative work, very different from traditional school assignments, since it will connect funding agents (banking professionals, investors, mentors and similar) with entrepreneurs and students. This DIGITAL LEARNING ENVIRONMENT BASED ON COLLABORATIVE LEARNING with financial agents is the core of our innovative proposal. Besides that, the project will deploy actions to empower HE teachers and entrepreneur coaches. Thus, the project will reach the following segments of people: university students, entrepreneurs, teachers, start-up incubators, financial agents for an estimated total of 840 direct participants and 14600 additional reached online. The main project activities will be oriented to the production of four intellectual outputs: 1) Practical cases in entrepreneurial finance for training purposes. 2) Digital Simulator for entrepreneurial finance (trainer’s tool). 3) Digital Simulator for entrepreneurial finance (self-learning tool). 4) Report on recommendations for entrepreneurial finance stakeholders and policy makers. The project implies cooperation of different type of organizations. The HE institutions and Banking/Financial sector will collaborate closely to ensure that we use appropriate content. Representative institutions will incorporate the tools into their trainings and will disseminate the project results properly. Entrepreneurial institutions will support the outputs creation attracting the attention of practitioners and professionals in the entrepreneurial field. The project pursues long term impact by providing HE lecturers, VET/adult training providers and Entrepreneurial institutions with innovative tools in order to spread the practical knowledge on entrepreneurial funding. It is of special interest to raise awareness on the different alternative sources of funding besides the traditional bank loans, such as crowdfunding, business angels, capital venture and so on, and offer current and future entrepreneurs practical training since it will also generate significant impact measured over time.
| Tipo de Documento: | Otro |
|---|---|
| Palabras Clave: | emprendedores, simulador, financiación, finanzas, practicas, plataforma digital |
| Clasificación temática: | Materias > Ciencias Sociales |
| Divisiones: | Universidad Europea del Atlántico > Investigación > Proyectos I+D+I |
| Depositado: | 07 Sep 2022 23:30 |
| Ultima Modificación: | 17 Oct 2024 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/3522 |
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Background Post-kala-azar dermal leishmaniasis (PKDL) is a skin condition that can become a complication in about 15 % of patients who have had kala-azar. Despite its significance, treatment options for PKDL are still limited. This systematic review and meta-analysis aim to evaluate the efficacy of amphotericin B for this condition. Methods PubMed, Embase, Cochrane, and Web of Science databases were searched for randomized controlled trials (RCTs) that reported the efficacy of Liposomal Amphotericin B in the treatment of PKDL. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Events per 100 observations with 95 % confidence intervals were performed for outcomes. Results Nine studies with 639 patients were included, the treatment durations ranging from 7 to 60 days. The mean age ranged from 9.2 to 31.0 years, and 359 patients were male. The PKDL treatment with liposomal amphotericin B resulted in a cure rate of 91.36 % (95 % CI: 76.60-97.15). However, a relapse was observed in 11.42 % (95 % CI: 6.20-20.8) of patients. Adverse events were common, with hepatic enzyme elevation (ALT/AST) being the most frequent (61.75 %; 95 % CI: 21.81–90.33), followed by fever in 29.93 % of cases (95 % CI: 5.09–77.30). Among the more serious side effects, decreased serum potassium was observed in 19.27 % (95 % CI: 3.84–58.82), and increased serum creatinine, indicative of nephrotoxicity, occurred in 15.08 % (95 % CI: 3.97–43.27). Nausea or vomiting, although less severe, affected 12.36 % of patients (95 % CI: 4.81–28.25). Conclusions These findings highlight that while liposomal amphotericin B is a potent therapeutic option for PKDL, its administration requires careful management and clinical vigilance to optimize outcomes and minimize risks.
Deivyd Vieira Silva Cavalcante mail , Lilia Maria Lima de Oliveira mail , Noor Husain mail , Beatriz Ximenes Mendes mail , Ana Clara Felix de Farias Santos mail , Luciana Borrigueiro mail , Lyria de Oliveira Rosa mail , Christian Ndikuryayo mail , Sarah Soares Amorim mail , Lalit Mohan mail , Fabiana Castro Porto Silva Lopes mail ,
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Enzymatic treatment shapes in vitro digestion pattern of phenolic compounds in mulberry juice
The health benefits of mulberry fruit are closely associated with its phenolic compounds. However, the effects of enzymatic treatments on the digestion patterns of these compounds in mulberry juice remain largely unknown. This study investigated the impact of pectinase (PE), pectin lyase (PL), and cellulase (CE) on the release of phenolic compounds in whole mulberry juice. The digestion patterns were further evaluated using an in vitro simulated digestion model. The results revealed that PE significantly increased chlorogenic acid content by 77.8 %, PL enhanced cyanidin-3-O-glucoside by 20.5 %, and CE boosted quercetin by 44.5 %. Following in vitro digestion, the phenolic compound levels decreased differently depending on the treatment, while cyanidin-3-O-rutinoside content increased across all groups. In conclusion, the selected enzymes effectively promoted the release of phenolic compounds in mulberry juice. However, during gastrointestinal digestion, the degradation of phenolic compounds surpassed their enhanced release, with effects varying based on the compound's structure.
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What works in financial education? Experimental evidence on program impact
Financial education is increasingly essential for safeguarding both individual and corporate well-being. This study systematically reviews global financial education experiments using a dual-method framework that integrates a deep learning classifier with advanced multivariate statistical techniques. Our analysis indicates that while short-term improvements in financial literacy are common, such gains tend to diminish over time without ongoing reinforcement. Moreover, the limited impact of digital innovations and monetary incentives suggests that successful financial education depends on more than simply deploying technological solutions or extrinsic rewards. Overall, this review provides valuable insights into the evolving landscape of financial education in a dynamic economic context and underscores the need for sustainable strategies that secure lasting improvements in financial literacy.
Gonzalo Llamosas García mail , Cristina Mazas Pérez-Oleaga mail cristina.mazas@uneatlantico.es,
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Epigallocatechin gallate (EGCG) is the most abundant polyphenol in tea. Owing to the different fermentation degrees, differences in polyphenol composition of water extracts of green tea, white tea, oolong tea, and black tea occur, and affect health value. This study revealed that the content of EGCG decreases with the increase in the degree of fermentation. In tea with a high fermentation degree, EGCG was stably present in the form of ammoniation to yield nitrogen-containing EGCG derivative (N-EGCG). The content of N-EGCG in tea was negatively correlated with the content of EGCG. Furthermore, the content of l-serine and L-threonine in tea was positively and negatively correlated with N-EGCG and EGCG levels, respectively, suggesting that they may participate in the formation of N-EGCG as nitrogen sources. This study proposes a new fermentation-induced polyphenol-amino acid synergistic mechanism, which provides a theoretical basis for the study of the biotransformation reaction mechanism of tea polyphenols.
Yuxuan Zhao mail , Jingyimei Liang mail , Wanning Ma mail , Mohamed A. Farag mail , Chunlin Li mail , Jianbo Xiao mail ,
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Single-cell omics for nutrition research: an emerging opportunity for human-centric investigations
Understanding how dietary compounds affect human health is challenged by their molecular complexity and cell-type–specific effects. Conventional multi-cell type (bulk) analyses obscure cellular heterogeneity, while animal and standard in vitro models often fail to replicate human physiology. Single-cell omics technologies—such as single-cell RNA sequencing, as well as single-cell–resolved proteomic and metabolomic approaches—enable high-resolution investigation of nutrient–cell interactions and reveal mechanisms at a single-cell resolution. When combined with advanced human-derived in vitro systems like organoids and organ-on-chip platforms, they support mechanistic studies in physiologically relevant contexts. This review outlines emerging applications of single-cell omics in nutrition research, emphasizing their potential to uncover cell-specific dietary responses, identify nutrient-sensitive pathways, and capture interindividual variability. It also discusses key challenges—including technical limitations, model selection, and institutional biases—and identifies strategic directions to facilitate broader adoption in the field. Collectively, single-cell omics offer a transformative framework to advance human-centric nutrition research.
Manuela Cassotta mail manucassotta@gmail.com, Yasmany Armas Diaz mail , Danila Cianciosi mail , Bei Yang mail , Zexiu Qi mail , Ge Chen mail , Santos Gracia Villar mail santos.gracia@uneatlantico.es, Luis Alonso Dzul López mail luis.dzul@uneatlantico.es, Giuseppe Grosso mail , José L. Quiles mail , Jianbo Xiao mail , Maurizio Battino mail maurizio.battino@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es,
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