Desarrollo de un modelo de dirección estratégica y de auditoria administrativa en el área de cartera de la empresa Agro veterinaria Juan Pablo en la ciudad de Sincelejo-Colombia

Tesis Materias > Ciencias Sociales Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster
Cerrado Español En la presente investigación se realiza un análisis estratégico del entorno tanto de factores externos como internos, que influyen o pueden llegar a influir positiva o negativamente en la empresa, identificándose dichos elementos, a través de la aplicación de la metodología PESTEL y FODA, que permita tener en cuenta el medio ambiente donde se desenvuelve la organización para el desarrollo y posterior implementación del modelo a cargo del empresario, en el área de cartera-cuentas por cobrar.El modelo desarrollado del planeación estratégica y auditoria administrativa, está fundamentado en los modelos propuestos por Fred David, Goodstein-Nolan – Pfeiffer y Kaplan-Norton, quienes toman elementos en común como lo son: Filosofía empresarial, planeación estratégica y cultura organizacional, auditoria.Se destaca que el modelo planteado está diseñado por fases, en las cuales deben involucrarse tanto el empresario como sus trabajadores, conformados en sus equipos de trabajo para el análisis interno y la creación de grupos para la construcción de la filosofía empresarial, toda vez que la organización no contaba inicialmente con ella, de igual forma sucede con el compromiso de cada actor en el proceso de aprobación de crédito y gestión cartera.Dentro de los resultados destacados se encuentran que las etapas de los procesos administrativos están centralizadas en la gerencia, al igual que la toma de decisiones relacionadas con aprobación de crédito y gestión de cartera, para lo cual no se cuenta con procedimientos estandarizados ni parámetros que permitan la medición o seguimiento de dichas actividades.Es por ello conforme al planteamiento del problema que la hipótesis planteada en la presente investigación se comprueba, haciéndose necesario el desarrollo de un modelo que conlleve a la planeación estratégica y auditoria administrativa que permita la planear, controlar, medir, estandarizar los proceso realizados para la aprobación y gestión de cartera cuentas por cobrar. metadata Estrada Mayoriano, Lina Marcela mail marceli1987.me@gmail.com (2022) Desarrollo de un modelo de dirección estratégica y de auditoria administrativa en el área de cartera de la empresa Agro veterinaria Juan Pablo en la ciudad de Sincelejo-Colombia. Masters thesis, SIN ESPECIFICAR.

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Resumen

En la presente investigación se realiza un análisis estratégico del entorno tanto de factores externos como internos, que influyen o pueden llegar a influir positiva o negativamente en la empresa, identificándose dichos elementos, a través de la aplicación de la metodología PESTEL y FODA, que permita tener en cuenta el medio ambiente donde se desenvuelve la organización para el desarrollo y posterior implementación del modelo a cargo del empresario, en el área de cartera-cuentas por cobrar.El modelo desarrollado del planeación estratégica y auditoria administrativa, está fundamentado en los modelos propuestos por Fred David, Goodstein-Nolan – Pfeiffer y Kaplan-Norton, quienes toman elementos en común como lo son: Filosofía empresarial, planeación estratégica y cultura organizacional, auditoria.Se destaca que el modelo planteado está diseñado por fases, en las cuales deben involucrarse tanto el empresario como sus trabajadores, conformados en sus equipos de trabajo para el análisis interno y la creación de grupos para la construcción de la filosofía empresarial, toda vez que la organización no contaba inicialmente con ella, de igual forma sucede con el compromiso de cada actor en el proceso de aprobación de crédito y gestión cartera.Dentro de los resultados destacados se encuentran que las etapas de los procesos administrativos están centralizadas en la gerencia, al igual que la toma de decisiones relacionadas con aprobación de crédito y gestión de cartera, para lo cual no se cuenta con procedimientos estandarizados ni parámetros que permitan la medición o seguimiento de dichas actividades.Es por ello conforme al planteamiento del problema que la hipótesis planteada en la presente investigación se comprueba, haciéndose necesario el desarrollo de un modelo que conlleve a la planeación estratégica y auditoria administrativa que permita la planear, controlar, medir, estandarizar los proceso realizados para la aprobación y gestión de cartera cuentas por cobrar.

Tipo de Documento: Tesis (Masters)
Palabras Clave: Procesos organizacionales, planeación estratégica, auditoria administrativa, cultura organizacional, filosofía empresarial, microempresas, modelos de administración, toma de decisiones, factores externos, factores internos.
Clasificación temática: Materias > Ciencias Sociales
Divisiones: Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster
Universidad Internacional Iberoamericana Puerto Rico > Docencia > Trabajos finales de Máster
Depositado: 03 Nov 2023 23:30
Ultima Modificación: 03 Nov 2023 23:30
URI: https://repositorio.uneatlantico.es/id/eprint/1839

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Effects of a 12-week multicomponent exercise programme on physical function in older adults with cancer: Study protocol for the ONKO-FRAIL randomised controlled trial

Introduction Cancer in older adults is often associated with functional limitations, geriatric syndromes, poor self-rated health, vulnerability, and frailty, and these conditions might worsen treatment-related side effects. Recent guidelines for patients with cancer during and after treatment have documented the beneficial effects of exercise to counteract certain side effects; however, little is known about the role of exercise during cancer treatment in older adults. Materials and Methods This is a multicentre randomised controlled trial in which 200 participants will be allocated to a control group or an intervention group (the sample size has been calculated to detect a clinical difference of 1 point in Short Physical Performance Battery (SPPB) score, assuming an α error of 0.05, a β error of 0.20, and a 10 % loss rate). Patients aged ≥70 years, diagnosed with any type of solid cancer and candidates for systemic treatment are eligible. Subjects in the intervention group are invited to participate in a 12-week supervised multicomponent exercise programme in addition to receiving usual care. Study assessments are conducted at baseline and three months. The primary outcome measure is physical function as assessed by the SPPB. Secondary outcome measures include comprehensive geriatric assessment scores (including social situation, basic and instrumental activities of daily living, cognitive function, depression, nutritional status, polypharmacy, geriatric syndromes, pain, and emotional distress), anthropometric characteristics, frailty status, physical fitness, physical activity, cognitive function, quality of life, fatigue, and nutritional status. Study assessments also include analysis of inflammatory, endocrine, and nutritional mediators in serum and plasma as potential frailty biomarkers at mRNA and protein levels and multiparametric flow cytometric analysis to measure immunosenescence markers on T and NK cells. Discussion This study seeks to extend our knowledge on exercise interventions during systemic anticancer treatment in patients over 70 years of age. Results from this research will guide the management of older adults during systemic treatment in hospitals seeking to enhance the standard of care.

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Efficacy of liposomal amphotericin B for treating post-kala-azar dermal leishmaniasis (PKDL): A systematic review and single-arm meta-analysis

Background Post-kala-azar dermal leishmaniasis (PKDL) is a skin condition that can become a complication in about 15 % of patients who have had kala-azar. Despite its significance, treatment options for PKDL are still limited. This systematic review and meta-analysis aim to evaluate the efficacy of amphotericin B for this condition. Methods PubMed, Embase, Cochrane, and Web of Science databases were searched for randomized controlled trials (RCTs) that reported the efficacy of Liposomal Amphotericin B in the treatment of PKDL. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Events per 100 observations with 95 % confidence intervals were performed for outcomes. Results Nine studies with 639 patients were included, the treatment durations ranging from 7 to 60 days. The mean age ranged from 9.2 to 31.0 years, and 359 patients were male. The PKDL treatment with liposomal amphotericin B resulted in a cure rate of 91.36 % (95 % CI: 76.60-97.15). However, a relapse was observed in 11.42 % (95 % CI: 6.20-20.8) of patients. Adverse events were common, with hepatic enzyme elevation (ALT/AST) being the most frequent (61.75 %; 95 % CI: 21.81–90.33), followed by fever in 29.93 % of cases (95 % CI: 5.09–77.30). Among the more serious side effects, decreased serum potassium was observed in 19.27 % (95 % CI: 3.84–58.82), and increased serum creatinine, indicative of nephrotoxicity, occurred in 15.08 % (95 % CI: 3.97–43.27). Nausea or vomiting, although less severe, affected 12.36 % of patients (95 % CI: 4.81–28.25). Conclusions These findings highlight that while liposomal amphotericin B is a potent therapeutic option for PKDL, its administration requires careful management and clinical vigilance to optimize outcomes and minimize risks.

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S-adenosylmethionine (SAM) is the main cellular methyl donor and a core product of one-carbon metabolism. Its balance with S-adenosylhomocysteine (SAH) defines methylation potential and shapes epigenetic and epitranscriptomic outputs. RNA N6-methyladenosine (m6A) directly depends on SAM and is controlled by a writer-reader-eraser system. This review summarizes how altered SAM supply, SAH accumulation, and shifts in the SAM/SAH ratio can reprogram m6A landscapes. These changes can occur in cancer, metabolic disease, inflammation, and neurodegeneration. We integrate metabolic control of SAM generation and consumption with regulation of METTL3/METTL14, WTAP and related cofactors, and the erasers FTO and ALKBH5. We also assess plant-derived bioactive compounds proposed to act on this coupling. Most phytochemicals do not behave as potent, selective m6A enzyme inhibitors. They more often act upstream by reshaping one-carbon metabolism, redox state, and protein expression. This profile contrasts with canonical synthetic inhibitors that block a single node with higher affinity and more predictable pharmacodynamics. Together, the evidence supports the SAM-m6A axis as a practical framework to connect nutrient state with RNA fate decisions. It also highlights key gaps for translation, including target engagement, dose-exposure alignment, and causal validation of m6A-dependent phenotypes.

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Innovative Application of Chatbots in Clinical Nutrition Education: The E+DIEting_Lab Experience in University Students

Background/Objectives: The growing integration of Artificial Intelligence (AI) and chatbots in health professional education offers innovative methods to enhance learning and clinical preparedness. This study aimed to evaluate the educational impact and perceptions in university students of Human Nutrition and Dietetics, regarding the utility, usability, and design of the E+DIEting_Lab chatbot platform when implemented in clinical nutrition training. Methods: The platform was piloted from December 2023 to April 2025 involving 475 students from multiple European universities. While all 475 students completed the initial survey, 305 finished the follow-up evaluation, representing a 36% attrition rate. Participants completed surveys before and after interacting with the chatbots, assessing prior experience, knowledge, skills, and attitudes. Data were analyzed using descriptive statistics and independent samples t-tests to compare pre- and post-intervention perceptions. Results: A total of 475 university students completed the initial survey and 305 the final evaluation. Most university students were females (75.4%), with representation from six languages and diverse institutions. Students reported clear perceived learning gains: 79.7% reported updated practical skills in clinical dietetics and communication were updated, 90% felt that new digital tools improved classroom practice, and 73.9% reported enhanced interpersonal skills. Self-rated competence in using chatbots as learning tools increased significantly, with mean knowledge scores rising from 2.32 to 2.66 and skills from 2.39 to 2.79 on a 0–5 Likert scale (p < 0.001 for both). Perceived effectiveness and usefulness of chatbots as self-learning tools remained positive but showed a small decline after use (effectiveness from 3.63 to 3.42; usefulness from 3.63 to 3.45), suggesting that hands-on experience refined, but did not diminish, students’ overall favorable views of the platform. Conclusions: The implementation and pilot evaluation of the E+DIEting_Lab self-learning virtual patient chatbot platform demonstrate that structured digital simulation tools can significantly improve perceived clinical nutrition competences. These findings support chatbot adoption in dietetics curricula and inform future digital education innovations.

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Objective: Children’s dietary choices are influenced by several factors, including parents’ modeling. The relation between parents’ psychosocial factors and their children’s level of adherence to the Mediterranean diet were explored. Methods: Food literacy, perceived barriers and enablers, and healthy-eating attitude following the Capability, Opportunity and Motivation (COM-B) model for behavioral change were evaluated in 2,011 participants in the DELICIOUS (UnDErstanding consumer food choices & promotion of healthy and sustainable Mediterranean Diet and LIfestyle in Children and adolescents through behavIOUral change actionS) project. Adherence to the Mediterranean diet was assessed through the KIDMED questionnaire. Beta coefficients and standard errors (SEs) were calculated through linear regression analyses. Results: Post-adjustment for potential confounding factors, results showed significant positive correlation between children’s adherence to the Mediterranean diet and parental food literacy [β (SE) = 0.180 (0.011)], perceived barriers and enablers [β (SE) = 0.135 (0.009)], and healthy-eating attitudes (divided into five constructs) [β (SE) = 0.069 (0.030), β (SE) = 0.037 (0.029), β (SE) = 0.162 (0.017), β (SE) = 0.147 (0.010), β (SE) = 0.158 (0.011)]. Individual dietary components of the Mediterranean diet were also associated with various psychosocial factors. Conclusion: These results confirm the importance of parental food literacy, perceived enablers and barriers to healthy-eating, health-eating attitude in their children’s adherence to the Mediterranean diet.

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