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¿Es el ángulo de fase una herramienta de pronóstico válida para la supervivencia de los pacientes con cáncer ?
Thesis Subjects > Biomedicine Europe University of Atlantic > Teaching > Final Degree Projects Cerrado Español metadata Madinabeitia Murillo, Jon mail jon.madinabeitia@alumnos.uneatlantico.es (2021) ¿Es el ángulo de fase una herramienta de pronóstico válida para la supervivencia de los pacientes con cáncer ? Diploma thesis, Universidad Europea del Atlántico.
Full text not available from this repository.Abstract
La bioimpedancia eléctrica es un método para la medida de la composición corporal basado en la capacidad del cuerpo humano para transmitir la corriente eléctrica, siendo por su bajo coste, su comodidad de uso y por ser poco invasivo el más extendido en la práctica clínica. Esta permite medir varios factores de interés en el ámbito clínico entre los que se encuentran la impedancia, la resistencia, reactancia, la capacitancia y por último el ángulo de fase. El principal objetivo del presente estudio fue estudiar la factibilidad del ángulo de fase para determinar el pronóstico de pacientes con diferentes tipos de cáncer. Para ello se incluyeron trabajos en español e inglés, posteriores al año 2004 y obtenidos de las bases de datos Pubmed y National Center for Biotechnology Information (NCBI). Finalmente, se consideraron elegibles para esta revisión 12 estudios que informaban sobre 2505 pacientes. Los trabajos seleccionados se llevaron a cabo en Estados Unidos, México y Corea del Sur. Siete estudios incluyeron una población con tipos específicos de cáncer, como el cáncer de mama, el cáncer de páncreas, el cáncer colorrectal, el cáncer de pulmón y el cáncer de cabeza y cuello. Para los estudios que incluyeron diferentes tipos de cáncer, el cáncer del tracto digestivo fue el tipo más común. Los estudios seleccionados para la revisión obtuvieron diferentes ángulos de fase dependiendo del tipo de cáncer y demostraron que, a mayor ángulo de fase, el pronóstico de vida era mayor. El ángulo de fase, derivado de la bioimpedancia, es un importante factor objetivo de predicción de la supervivencia para los pacientes con diferentes tipos de patologías, pero se necesitan estudios similares de otros tipos de cáncer con tamaños de muestra suficientemente grandes para seguir validando la importancia del pronóstico del ángulo de fase en los entornos clínicos.
| Item Type: | Thesis (Diploma) |
|---|---|
| Uncontrolled Keywords: | Bioimpedancia, Cáncer, Ángulo de fase, Bioimpedancia eléctrica, Salud celular, Pronóstico, Mortalidad. |
| Subjects: | Subjects > Biomedicine |
| Divisions: | Europe University of Atlantic > Teaching > Final Degree Projects |
| Date Deposited: | 06 Oct 2021 23:55 |
| Last Modified: | 06 Oct 2021 23:55 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/309 |
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Abstract: Sports injuries can affect the performance of athletes. For this reason, functional tests are used for injury assessment and prevention, analyzing physical or physiological imbalances and detecting asymmetries. The main aim of this study was to detect the asymmetries in the upper limbs (right and left arms) in athletes, using the OctoBalance Test (OB), depending on the stage of the season. Two hundred and fifty-two participants (age: 23.33 ± 8.96 years old; height: 178.63 ± 11.12 cm; body mass: 80.28 ± 17.61 kg; body mass index: 24.88 ± 4.58; sports experience: 12.52 ± 6.28 years), practicing different sports (rugby, athletics, football, swimming, handball, triathlon, basketball, hockey, badminton and volleyball), assessed with the OB in medial, superolateral, and inferolateral directions in both arms, in four moments of the season (May 2017, September 2017, February 2018 and May 2018). ANOVA test was used with repeated measures with a p ≤ 0.05, for the analysis of the different studied variances. Significant differences were found (p = 0.021) in the medial direction of the left arm, between the first (May 2017) and fourth stages (May 2018), with values of 71.02 ± 7.15 cm and 65.03 ± 7.66 cm. From the detection of asymmetries, using the OB to measure, in the medial, superolateral and inferolateral directions, mobility and balance can be assessed. In addition, it is possible to observe functional imbalances, as a risk factor for injury, in each of the stages into which the season is divided, which will help in the prevention of injuries and in the individualization of training.
Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Antonio Bores-Cerezal mail antonio.bores@uneatlantico.es, Marcos Mecías-Calvo mail marcos.mecias@uneatlantico.es, Martín Barcala Furelos mail martin.barcala@uneatlantico.es, Silvia Aparicio Obregón mail silvia.aparicio@uneatlantico.es, Julio Calleja-González mail ,
Velarde-Sotres
Blockchain Interoperability: Towards a Sustainable Payment System
The highly fragmented blockchain and cryptocurrency ecosystem necessitates interoperability mechanisms as a requirement for blockchain-technology acceptance. The immediate implication of interchain interoperability is automatic swapping between cryptocurrencies. We performed a systematic review of the existing literature on Blockchain interoperability and atomic cross-chain transactions. We investigated different blockchain interoperability approaches, including industrial solutions, categorized them and identified the key mechanisms used, and list several example projects for each category. We focused on the atomic transactions between blockchain, a process also known as atomic swap. Furthermore, we studied recent implementations along with architectural approaches for atomic swap and deduced research issues and challenges in cross-chain interoperability and atomic swap. Atomic swap can instantly transfer tokens and significantly reduce the associated costs without using any centralized authority, and thus facilitates the development of a sustainable payment system for wider financial inclusion.
Debasis Mohanty mail , Divya Anand mail , Hani Moaiteq Aljahdali mail , Santos Gracia Villar mail santos.gracia@uneatlantico.es,
Mohanty
The articular evaluation of range of motion (ROM) is currently used to observe imbalance or limitations as possible risk factors or predispositions to suffer future injures. The main aim of this study is to verify the concurrent validity, reliability and reproducibility of the OctoBalance Test (OB) as a valid and reliable tool to measure articular ROM of the upper limb compared to the modified-Upper Quarter Y-Balance Test (mUQYBT). The twenty-five participants were male athletes. All of them were assessed with OB and mUQYBT in medial, superolateral, and inferolateral directions in both right and left arms with a three-minute break during these attempts. The process was repeated a second time with a week gap between measurements. Pearson correlation and linear logarithmic regression were used to examine the relationship between scores obtained with OB and mUQYBT. In order to verify the reliability, the intraclass correlation coefficient (ICC) was used (3.1). Concordance and reproducibility were assessed using Bland-Altman's graph. A perfect correlation and an almost linear logarithmic regression (R 2 = 0.97) were observed between both measurement systems, with values of 73.531 ± 21.226 cm in mUQYBT and 69.541 ± 16.330 cm in OB. The differences were minimal between week one and week two. The assessment with Bland's graph showed the concordance and reproducibility of scores, showing the dispersion and the upper and lower limits. OB is shown as valid in comparison to the other test as a reliable and reproducible tool for the assessment of the articular ROM in the upper limb, and it could be used for the evaluation of injuries.
Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Antonio Bores-Cerezal mail antonio.bores@uneatlantico.es, Marcos Mecías-Calvo mail marcos.mecias@uneatlantico.es, Stefanía Carvajal-Altamiranda mail stefania.carvajal@uneatlantico.es, Julio Calleja-González mail ,
Velarde-Sotres
Validity and Reliability of a New Device to Measure Type of Actions in Indoor Sports
The purpose of this study was to analyze the validity and the reliability of the intensity ranges, number of actions and changes of direction measured by a commercial inertial measurement unit. Eleven elite youth futsal players performed a circuit with different type of displacements as sprinting, running at low-medium intensity, standing up and changes of direction. Data recorded by the Overtraq system were compared with video-analyzer during the six trials of each player. Standard error mean, Intraclass Correlation Coeficient and Coefficient of variation, were calculated to analyze the reliability of the device, as well as the Root Mean Square Error and Confidence Interval with correlation of Pearson for its validity. The results reported good validity for three intensity ranges (R2>0.7) with high reliability (Intraclass Correlation Coeficient: 0.8–0.9), especially for high intensity actions (Intraclass Correlation Coeficient: 0.95, Coefficient of Variation: 3.06%). Furthermore, the validity for the number of different actions was almost perfect (96.3–100%), with only small differences regarding changes of activity (mean error: 2.0%). The Overtraq system can be considered as a valid and reliable technology for measuring and monitoring actions at different intensities and changes of direction in futsal, likewise common actions for other indoor sports.
Carlos Lago-Fuentes mail carlos.lago@uneatlantico.es, Paolo Aiello mail , Mauro Testa mail , Iker Muñoz mail iker.munoz@uneatlantico.es, Marcos Macías Calvo mail marcos.macías@uneatlantico.es,
Lago-Fuentes
Antimony is a toxic element whose concentration in soil and water has been rising due to anthropogenic activities. This study focuses on its accumulation in leaves of Dittrichia viscosa growing in soils of an abandoned Sb mine, and the effect on oxidant/antioxidant systems and photosynthetic efficiency. The results showed leaves to have a high Sb accumulation capacity. The amount of total chlorophyll decreased depending on Sb concentration and of carotenoids increased slightly, with a consequent increase in carotenoid/chlorophyll ratio. Photosynthetic efficiency was unaffected. The amount of O .−2 rose, although there was no increase in cell membrane damage, with lipid peroxidation levels being similar to normal. This response may be due to considerable increases that were observed in total phenolics, PPO activity, and enzymatic antioxidant system. SOD, POX, and DHAR activities increased in response to increased Sb amounts in leaves. The ascorbate/glutathione cycle was also affected, with strong increases observed in all of its components, and consequent increases in total contents of the ascorbate and glutathione pools. However, the ratio between reduced and oxidized forms declined, reflecting an imbalance between the two, especially that between GSH and GSSG. Efficient detoxification of Sb may take place either through increases in phenolics, carotenoids, and components of the glutathione–ascorbate cycle or through the enzymatic antioxidant system. Since Dittrichia viscosa accumulates large amounts of Sb without suffering oxidative damage, it could be used for phytoremediation.
Ignacio Garrido mail , A. Ortega mail , Marcos Hernández Suárez mail marcos.hernandez@uneatlantico.es, L. Fernández-Pozo mail , J. Cabezas mail , F. Espinosa mail ,
Garrido