Consolidação do processo de Gestão compartilhada na Fundação da Criança e do Adolescente – FUNAC
Tesis Materias > Ciencias Sociales Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster Cerrado Portugués O presente estudo, de caráter qualitativo, objetivou analisar o nível de consolidação do processo de Gestão compartilhada na Fundação da Criança e do Adolescente, órgão de atendimento ao adolescente em conflito com a Lei e o sistema educacional público – Secretaria de Estado de Educação, no Estado do Maranhão, a partir do paradigma da proteção integral. À luz do SINASE e demais referenciais legais buscou-se identificar quais os objetivos e lineamentos para a implementação da cogestão na instituição; descrever as maneiras de aplicação da cogestão; comprovar como tem se atingido os objetivos; identificar fortalezas, debilidades e demandas no processo de cogestão institucional e investigar se há participação efetiva da família, no processo de gestão escolar por meio de conselhos de classe estabelecidos conforme legislação pertinente. Para tanto utilizamos múltiplas fontes de dados empregando a observação; registro de campo através de um roteiro de entrevista, onde foram entrevistados a Presidência da Fundação executora e técnicos responsáveis pelo acompanhamento aos adolescentes internos; revisão bibliográfica; leituras e releituras sobre leis e autores que desenvolvem trabalhos na área da socioeducação; identificando as características da participação dos diversos segmentos que compõem o Sistema de Garantía de Direitos; revisitando os conceitos apresentados e sua interseção com o modelo de gestão adotado pelo Sistema Nacional de Atendimento Socioeducativo. Ficou evidenciado que as Políticas Sociais no País, ainda se acham em luta contra hegemônica, isso sentido a partir da heterogeneidade dos avanços e retrocessos identificados, especificamente no tocante à educação, no contexto de privação de liberdade. No que concerne à participação das famílias e comunidade, estas se mantêm distantes necessitando haver uma agenda explicitando as obrigações mútuas. Pretende-se, neste estudo contribuir para ensejar um processo de aprofundamento sobre o tema, de forma a ampliar o debate e construção de estratégias que possibilitem adoção de instrumentos de controle e pactuação entre os orgãos gestores, vez que a complexidade e condução do processo escolar dentro da Instituição requer, sobretudo o emprego e adoção de práticas objetivas claramente definidas. metadata Pereira Baquil, Dione Maria mail ens.dione@gmail.com (2022) Consolidação do processo de Gestão compartilhada na Fundação da Criança e do Adolescente – FUNAC. Masters thesis, SIN ESPECIFICAR.
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O presente estudo, de caráter qualitativo, objetivou analisar o nível de consolidação do processo de Gestão compartilhada na Fundação da Criança e do Adolescente, órgão de atendimento ao adolescente em conflito com a Lei e o sistema educacional público – Secretaria de Estado de Educação, no Estado do Maranhão, a partir do paradigma da proteção integral. À luz do SINASE e demais referenciais legais buscou-se identificar quais os objetivos e lineamentos para a implementação da cogestão na instituição; descrever as maneiras de aplicação da cogestão; comprovar como tem se atingido os objetivos; identificar fortalezas, debilidades e demandas no processo de cogestão institucional e investigar se há participação efetiva da família, no processo de gestão escolar por meio de conselhos de classe estabelecidos conforme legislação pertinente. Para tanto utilizamos múltiplas fontes de dados empregando a observação; registro de campo através de um roteiro de entrevista, onde foram entrevistados a Presidência da Fundação executora e técnicos responsáveis pelo acompanhamento aos adolescentes internos; revisão bibliográfica; leituras e releituras sobre leis e autores que desenvolvem trabalhos na área da socioeducação; identificando as características da participação dos diversos segmentos que compõem o Sistema de Garantía de Direitos; revisitando os conceitos apresentados e sua interseção com o modelo de gestão adotado pelo Sistema Nacional de Atendimento Socioeducativo. Ficou evidenciado que as Políticas Sociais no País, ainda se acham em luta contra hegemônica, isso sentido a partir da heterogeneidade dos avanços e retrocessos identificados, especificamente no tocante à educação, no contexto de privação de liberdade. No que concerne à participação das famílias e comunidade, estas se mantêm distantes necessitando haver uma agenda explicitando as obrigações mútuas. Pretende-se, neste estudo contribuir para ensejar um processo de aprofundamento sobre o tema, de forma a ampliar o debate e construção de estratégias que possibilitem adoção de instrumentos de controle e pactuação entre os orgãos gestores, vez que a complexidade e condução do processo escolar dentro da Instituição requer, sobretudo o emprego e adoção de práticas objetivas claramente definidas.
| Tipo de Documento: | Tesis (Masters) |
|---|---|
| Palabras Clave: | PALAVRAS -CHAVE: CONSOLIDAÇÃO, GESTÃO COMPARTILHADA, SOCIOEDUCAÇÃO , SINASE SINASE |
| Clasificación temática: | Materias > Ciencias Sociales |
| Divisiones: | Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster |
| Depositado: | 15 Abr 2024 23:30 |
| Ultima Modificación: | 15 Abr 2024 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/2752 |
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Enzymatic treatment shapes in vitro digestion pattern of phenolic compounds in mulberry juice
The health benefits of mulberry fruit are closely associated with its phenolic compounds. However, the effects of enzymatic treatments on the digestion patterns of these compounds in mulberry juice remain largely unknown. This study investigated the impact of pectinase (PE), pectin lyase (PL), and cellulase (CE) on the release of phenolic compounds in whole mulberry juice. The digestion patterns were further evaluated using an in vitro simulated digestion model. The results revealed that PE significantly increased chlorogenic acid content by 77.8 %, PL enhanced cyanidin-3-O-glucoside by 20.5 %, and CE boosted quercetin by 44.5 %. Following in vitro digestion, the phenolic compound levels decreased differently depending on the treatment, while cyanidin-3-O-rutinoside content increased across all groups. In conclusion, the selected enzymes effectively promoted the release of phenolic compounds in mulberry juice. However, during gastrointestinal digestion, the degradation of phenolic compounds surpassed their enhanced release, with effects varying based on the compound's structure.
Peihuan Luo mail , Jian Ai mail , Qiongyao Wang mail , Yihang Lou mail , Zhiwei Liao mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Elwira Sieniawska mail , Weibin Bai mail , Lingmin Tian mail ,
Luo
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A novel machine learning-based proposal for early prediction of endometriosis disease
Background Endometriosis is one of the causes of female infertility, with some studies estimating its prevalence at around 10 % of reproductive-age women worldwide and between 30 and 50 % in symptomatic women. However, its diagnosis is complex and often delayed, highlighting the need for more accessible and accurate diagnostic methods. The difficulty lies in its diverse etiology and the variability of symptoms among those affected. Methods This study proposes a predictive model based on supervised machine learning for the early identification of endometriosis, providing support for decision-making by healthcare professionals. For this purpose, an anonymised dataset of 5,143 female patients diagnosed with endometriosis at the private fertility clinic Inebir was used. The model integrates clinical records and genetic analysis through supervised machine learning algorithms, focusing on clinical variables and pathogenic and potentially pathogenic genetic variants. Results The developed predictive model achieves high accuracy in identifying the presence of endometriosis, highlighting the importance of combining clinical and genetic data in diagnosis. The integration of this data into the DELFOS platform, a clinical decision support system, demonstrates the utility of machine learning in improving the diagnosis of endometriosis. Conclusions The findings underscore the potential of clinical and genetic factors in the early diagnosis of endometriosis using supervised machine learning algorithms. This study contributes to the classification of clinical variables that influence endometriosis, offering a valuable tool for clinicians in making therapeutic and management decisions for their female patients.
Elena Enamorado-Díaz mail , Leticia Morales-Trujillo mail , Julián-Alberto García-García mail , Ana Teresa Marcos Rodríguez mail anateresa.marcos@uneatlantico.es, José Manuel Navarro-Pando mail jose.navarro@uneatlantico.es, María-José Escalona-Cuaresma mail ,
Enamorado-Díaz
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Detecting hate in diversity: a survey of multilingual code-mixed image and video analysis
The proliferation of damaging content on social media in today’s digital environment has increased the need for efficient hate speech identification systems. A thorough examination of hate speech detection methods in a variety of settings, such as code-mixed, multilingual, visual, audio, and textual scenarios, is presented in this paper. Unlike previous research focusing on single modalities, our study thoroughly examines hate speech identification across multiple forms. We classify the numerous types of hate speech, showing how it appears on different platforms and emphasizing the unique difficulties in multi-modal and multilingual settings. We fill research gaps by assessing a variety of methods, including deep learning, machine learning, and natural language processing, especially for complicated data like code-mixed and cross-lingual text. Additionally, we offer key technique comparisons, suggesting future research avenues that prioritize multi-modal analysis and ethical data handling, while acknowledging its benefits and drawbacks. This study attempts to promote scholarly research and real-world applications on social media platforms by acting as an essential resource for improving hate speech identification across various data sources.
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Raza Ur Rehman
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Alzheimer's disease (AD) involves β-amyloid plaques and tau hyperphosphorylation, driven by oxidative stress and neuroinflammation. Cyclooxygenase-2 (COX-2) and acetylcholinesterase (AChE) activities exacerbate AD pathology. Olive leaf (OL) extracts, rich in bioactive compounds, offer potential therapeutic benefits. This study aimed to assess the anti-inflammatory, anti-cholinergic, and antioxidant effects of three OL extracts (low, mid, and high bioactive content) in vitro and their protective effects against AD-related proteinopathies in Caenorhabditis elegans models. OL extracts were characterized for phenolic composition, AChE and COX-2 inhibition, as well as antioxidant capacity. Their effects on intracellular and mitochondrial reactive oxygen species (ROS) were tested in C. elegans models expressing human Aβ and tau proteins. Gene expression analyses examined transcription factors (DAF-16, skinhead [SKN]-1) and their targets (superoxide dismutase [SOD]-2, SOD-3, GST-4, and heat shock protein [HSP]-16.2). High-OL extract demonstrated superior AChE and COX-2 inhibition and antioxidant capacity. Low- and high-OL extracts reduced Aβ aggregation, ROS levels, and proteotoxicity via SKN-1/NRF-2 and DAF-16/FOXO pathways, whereas mid-OL showed moderate effects through proteostasis modulation. In tau models, low- and high-OL extracts mitigated mitochondrial ROS levels via SOD-2 but had limited effects on intracellular ROS levels. High-OL extract also increased GST-4 levels, whereas low and mid extracts enhanced GST-4 levels. OL extracts protect against AD-related proteinopathies by modulating oxidative stress, inflammation, and proteostasis. High-OL extract showed the most promise for nutraceutical development due to its robust phenolic profile and activation of key antioxidant pathways. Further research is needed to confirm long-term efficacy.
Jose M. Romero‐Marquez mail , María D. Navarro‐Hortal mail , Alfonso Varela‐López mail , Rubén Calderón Iglesias mail ruben.calderon@uneatlantico.es, Juan G. Puentes mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Cristina Sánchez‐González mail , Jianbo Xiao mail , Roberto García‐Ruiz mail , Sebastián Sánchez mail , Tamara Y. Forbes‐Hernández mail , José L. Quiles mail jose.quiles@uneatlantico.es,
Romero‐Marquez
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Garlic is a horticultural product highly valued for its culinary and medicinal attributes. The aim of this study was to evaluate the composition of a garlic hydrophilic extract as well as the influence on redox biology, Alzheimer's Disease (AD) markers and aging, using Caenorhabditis elegans as experimental model. The extract was rich in sulfur compounds, highlighting the presence of other compounds like phenolics, and the antioxidant property was corroborated. Regarding AD markers, the acetylcholinesterase inhibitory capacity was demonstrated in vitro. Although the extract did not modify the amyloid β-induced paralysis degree, it was able to improve, in a dose-dependent manner, some locomotive parameters affected by the hyperphosphorylated tau protein in C. elegans. It could be related to the effect found on GFP-transgenic stains, mainly regarding to the increase in the gene expression of HSP-16.2. Moreover, an initial investigation into the aging process revealed that the extract successfully inhibited the accumulation of intracellular and mitochondrial reactive oxygen species in aged worms. These results provide valuable insights into the multifaceted impact of garlic extract, particularly in the context of aging and neurodegenerative processes. This study lays a foundation for further research avenues exploring the intricate molecular mechanisms underlying garlic effects and its translation into potential therapeutic interventions for age-related neurodegenerative conditions.
María D. Navarro‐Hortal mail , Jose M. Romero‐Marquez mail , Johura Ansary mail , Cristina Montalbán‐Hernández mail , Alfonso Varela‐López mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Jianbo Xiao mail , Rubén Calderón Iglesias mail ruben.calderon@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Cristina Sánchez‐González mail , Tamara Y. Forbes‐Hernández mail , José L. Quiles mail jose.quiles@uneatlantico.es,
Navarro‐Hortal