Artículo Materias > Psicología Universidad Europea del Atlántico > Investigación > Artículos y libros Cerrado Inglés People living with HIV (PLWH) must face a wide variety of stress factors, both physical and psychological, that interact with each other, depleting their resources to cope with the ensuing challenges. As a result, depression and psychological stress are very common among those in this population. The aim of this chapter is to show the potential therapeutic effects that mindfulness-based cognitive therapy (MBCT) has on promoting their well-being. To accomplish this, first we briefly describe the current issues that this population, as well as their caretakers, must face. Also, we will present the rationale for applying MBCT in PLWH and the specific modifications that will help to make the program successful. Next, in order to illustrate the way in which the program can be adapted to the challenges of PLWH, we present two clinical cases. Subsequently, we review the special considerations surrounding the implementation of MBCT. With the goal of incorporating all of the research that has been carried out so far, we propose a meta-model that identifies a common structure that attempts to explain the mechanisms of change that underlie the effects on well-being of mindfulness-based interventions (MBIs). The model identifies three mechanisms of change: attention, meta-awareness, and self-regulation, along with their main brain-related areas, and explains how they are interrelated. Finally, we suggest future directions to continue expanding MBCT research. metadata González-García, Marian; Borràs, Xavier; López, Javier González y McNeil, Kim Griffin mail marian.gonzalez@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2016) Mindfulness-Based Cognitive Therapy application for People Living with Chronic Disease: the case of HIV. Mindfulness-Based Cognitive Therapy. pp. 83-103.