Pacing and packing behaviour in elite and world record performances at Berlin marathon
Artículo Materias > Educación física y el deporte Universidad Europea del Atlántico > Investigación > Artículos y libros Cerrado Inglés The aim of this study was to compare pacing and packing behaviours between sex and performance level at elite Berlin marathon races. Official electronic split and finishing times from 279 (149 male and 130 female) marathon performances, including 5 male world records, were obtained from 11 Berlin marathon races held from 2008 to 2018, and from two previous world records and the second world all-time fastest performance also achieved at that same Berlin course. Male performances displaying an even pacing behaviour were significantly faster than those adopting a positive behaviour (p < 0.001; d = 0.75). Male world records were characterized by even profiles with fast endspurts, being especially remarkable at world all-time two fastest performances which were assisted by the use of a new shoe technology. Female marathon runners decreased their speed less than men during the second half marathon and especially from the 35th km onwards (p < 0.001; 0.51 ≤ d ≤ 0.55). The latest race stages were usually run individually in both sexes. Significant pace differences between performance groups at every race segment were found in women (p < 0.01; 1.0 ≤ d ≤ 2.0), who also covered an important part of the race alone. Prior to participation in meet marathon races such as Berlin marathon, elite runners should select the group that they will join during the race according to their current performance level as a preassigned pace set by a pacemaker will be adopted. Therefore, they could follow an even rather than positive pacing behaviour which will allow them to achieve a more optimal performance. metadata Muñoz-Pérez, Iker; Lago-Fuentes, Carlos; Mecías-Calvo, Marcos y Casado, Arturo mail SIN ESPECIFICAR, carlos.lago@uneatlantico.es, marcos.mecias@uneatlantico.es, SIN ESPECIFICAR (2022) Pacing and packing behaviour in elite and world record performances at Berlin marathon. European Journal of Sport Science. pp. 1-8. ISSN 1746-1391
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The aim of this study was to compare pacing and packing behaviours between sex and performance level at elite Berlin marathon races. Official electronic split and finishing times from 279 (149 male and 130 female) marathon performances, including 5 male world records, were obtained from 11 Berlin marathon races held from 2008 to 2018, and from two previous world records and the second world all-time fastest performance also achieved at that same Berlin course. Male performances displaying an even pacing behaviour were significantly faster than those adopting a positive behaviour (p < 0.001; d = 0.75). Male world records were characterized by even profiles with fast endspurts, being especially remarkable at world all-time two fastest performances which were assisted by the use of a new shoe technology. Female marathon runners decreased their speed less than men during the second half marathon and especially from the 35th km onwards (p < 0.001; 0.51 ≤ d ≤ 0.55). The latest race stages were usually run individually in both sexes. Significant pace differences between performance groups at every race segment were found in women (p < 0.01; 1.0 ≤ d ≤ 2.0), who also covered an important part of the race alone. Prior to participation in meet marathon races such as Berlin marathon, elite runners should select the group that they will join during the race according to their current performance level as a preassigned pace set by a pacemaker will be adopted. Therefore, they could follow an even rather than positive pacing behaviour which will allow them to achieve a more optimal performance.
| Tipo de Documento: | Artículo |
|---|---|
| Palabras Clave: | Competition; endurance; gender; performance |
| Clasificación temática: | Materias > Educación física y el deporte |
| Divisiones: | Universidad Europea del Atlántico > Investigación > Artículos y libros |
| Depositado: | 05 Sep 2022 23:30 |
| Ultima Modificación: | 17 Jul 2023 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/3485 |
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Enzymatic treatment shapes in vitro digestion pattern of phenolic compounds in mulberry juice
The health benefits of mulberry fruit are closely associated with its phenolic compounds. However, the effects of enzymatic treatments on the digestion patterns of these compounds in mulberry juice remain largely unknown. This study investigated the impact of pectinase (PE), pectin lyase (PL), and cellulase (CE) on the release of phenolic compounds in whole mulberry juice. The digestion patterns were further evaluated using an in vitro simulated digestion model. The results revealed that PE significantly increased chlorogenic acid content by 77.8 %, PL enhanced cyanidin-3-O-glucoside by 20.5 %, and CE boosted quercetin by 44.5 %. Following in vitro digestion, the phenolic compound levels decreased differently depending on the treatment, while cyanidin-3-O-rutinoside content increased across all groups. In conclusion, the selected enzymes effectively promoted the release of phenolic compounds in mulberry juice. However, during gastrointestinal digestion, the degradation of phenolic compounds surpassed their enhanced release, with effects varying based on the compound's structure.
Peihuan Luo mail , Jian Ai mail , Qiongyao Wang mail , Yihang Lou mail , Zhiwei Liao mail , Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es, Elwira Sieniawska mail , Weibin Bai mail , Lingmin Tian mail ,
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A novel machine learning-based proposal for early prediction of endometriosis disease
Background Endometriosis is one of the causes of female infertility, with some studies estimating its prevalence at around 10 % of reproductive-age women worldwide and between 30 and 50 % in symptomatic women. However, its diagnosis is complex and often delayed, highlighting the need for more accessible and accurate diagnostic methods. The difficulty lies in its diverse etiology and the variability of symptoms among those affected. Methods This study proposes a predictive model based on supervised machine learning for the early identification of endometriosis, providing support for decision-making by healthcare professionals. For this purpose, an anonymised dataset of 5,143 female patients diagnosed with endometriosis at the private fertility clinic Inebir was used. The model integrates clinical records and genetic analysis through supervised machine learning algorithms, focusing on clinical variables and pathogenic and potentially pathogenic genetic variants. Results The developed predictive model achieves high accuracy in identifying the presence of endometriosis, highlighting the importance of combining clinical and genetic data in diagnosis. The integration of this data into the DELFOS platform, a clinical decision support system, demonstrates the utility of machine learning in improving the diagnosis of endometriosis. Conclusions The findings underscore the potential of clinical and genetic factors in the early diagnosis of endometriosis using supervised machine learning algorithms. This study contributes to the classification of clinical variables that influence endometriosis, offering a valuable tool for clinicians in making therapeutic and management decisions for their female patients.
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Alzheimer's disease (AD) involves β-amyloid plaques and tau hyperphosphorylation, driven by oxidative stress and neuroinflammation. Cyclooxygenase-2 (COX-2) and acetylcholinesterase (AChE) activities exacerbate AD pathology. Olive leaf (OL) extracts, rich in bioactive compounds, offer potential therapeutic benefits. This study aimed to assess the anti-inflammatory, anti-cholinergic, and antioxidant effects of three OL extracts (low, mid, and high bioactive content) in vitro and their protective effects against AD-related proteinopathies in Caenorhabditis elegans models. OL extracts were characterized for phenolic composition, AChE and COX-2 inhibition, as well as antioxidant capacity. Their effects on intracellular and mitochondrial reactive oxygen species (ROS) were tested in C. elegans models expressing human Aβ and tau proteins. Gene expression analyses examined transcription factors (DAF-16, skinhead [SKN]-1) and their targets (superoxide dismutase [SOD]-2, SOD-3, GST-4, and heat shock protein [HSP]-16.2). High-OL extract demonstrated superior AChE and COX-2 inhibition and antioxidant capacity. Low- and high-OL extracts reduced Aβ aggregation, ROS levels, and proteotoxicity via SKN-1/NRF-2 and DAF-16/FOXO pathways, whereas mid-OL showed moderate effects through proteostasis modulation. In tau models, low- and high-OL extracts mitigated mitochondrial ROS levels via SOD-2 but had limited effects on intracellular ROS levels. High-OL extract also increased GST-4 levels, whereas low and mid extracts enhanced GST-4 levels. OL extracts protect against AD-related proteinopathies by modulating oxidative stress, inflammation, and proteostasis. High-OL extract showed the most promise for nutraceutical development due to its robust phenolic profile and activation of key antioxidant pathways. Further research is needed to confirm long-term efficacy.
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Garlic is a horticultural product highly valued for its culinary and medicinal attributes. The aim of this study was to evaluate the composition of a garlic hydrophilic extract as well as the influence on redox biology, Alzheimer's Disease (AD) markers and aging, using Caenorhabditis elegans as experimental model. The extract was rich in sulfur compounds, highlighting the presence of other compounds like phenolics, and the antioxidant property was corroborated. Regarding AD markers, the acetylcholinesterase inhibitory capacity was demonstrated in vitro. Although the extract did not modify the amyloid β-induced paralysis degree, it was able to improve, in a dose-dependent manner, some locomotive parameters affected by the hyperphosphorylated tau protein in C. elegans. It could be related to the effect found on GFP-transgenic stains, mainly regarding to the increase in the gene expression of HSP-16.2. Moreover, an initial investigation into the aging process revealed that the extract successfully inhibited the accumulation of intracellular and mitochondrial reactive oxygen species in aged worms. These results provide valuable insights into the multifaceted impact of garlic extract, particularly in the context of aging and neurodegenerative processes. This study lays a foundation for further research avenues exploring the intricate molecular mechanisms underlying garlic effects and its translation into potential therapeutic interventions for age-related neurodegenerative conditions.
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Novel hybrid transfer neural network for wheat crop growth stages recognition using field images
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