Factores causales de infertiildad presentes en mujeres guatemaltecas con sobrepeso y obesidad
Tesis Materias > Biomedicina Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster Cerrado Español La infertilidad y la obesidad son dos enfermedades cuya prevalencia mundial se encuentra en acenso tanto en hombres como en mujeres y según el desarrollo socioeconómico de un país es posible observar personas obesas y con sobrepeso desde muy temprana edad. La infertilidad por otro lado es más frecuente en personas mayores de 35 años. La combinación de un índice de masa corporal elevado e infertilidad ocasiona que las personas que consultan por infertilidad presenten un panorama menos favorable. Los factores causales de infertilidad femenina pueden verse afectados por la asociación de un índice de masa corporal elevado, por lo tanto, el objetivo principal de esta investigación es identificar los factores causales de infertilidad femenina que presentaron mujeres que utilizaron técnicas de reproducción asistida y que presentaron un índice de masa corporal elevado. Para esto se llevó a cabo una investigación descriptiva de tipo transversal utilizando una metodología cuantitativa. Los hallazgos se realizaron mediante la revisión documental de expedientes clínicos del Centro de Reproducción Humana, CER, Guatemala, en donde se realizó el llenado de un instrumento de recolección de datos el cual posteriormente fue analizado por medio de estadística descriptiva.Fue posible identificar siete factores causales de infertilidad femenina, los cuales corresponden a los factores ovárico, tubárico, uterino, hormonal, peritoneal, cervical y ambiental. Se encontraron casos en los que no fue posible identificar un factor específico. El factor más frecuente es el factor ovárico. Las pacientes menores de 34 años presentan mayor frecuencia de síndrome de ovario poliquístico y obstrucción tubárica mientras que las mayores de 35 años presentan la baja reserva ovárica y la realización de esterilización tubárica como principales causas de infertilidad. El sobrepeso estuvo presente en mayor frecuencia en todos los factores encontrados. La técnica de reproducción asistida más utilizada fue la fertilización in vitro, seguida de la inseminación intrauterina. Se concluye, por lo tanto, que el factor ovárico es el principal factor causal de infertilidad en la mujer guatemalteca con obesidad y con sobrepeso, la obstrucción tubárica es el segundo más frecuente y la miomatosis uterina el tercero. Los factores ambiental y cervical se encontraron en combinación en todas las ocasiones. metadata Turcios Sandoval, Carlos Alberto mail nobfriend@yahoo.com (2022) Factores causales de infertiildad presentes en mujeres guatemaltecas con sobrepeso y obesidad. Masters thesis, SIN ESPECIFICAR.
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La infertilidad y la obesidad son dos enfermedades cuya prevalencia mundial se encuentra en acenso tanto en hombres como en mujeres y según el desarrollo socioeconómico de un país es posible observar personas obesas y con sobrepeso desde muy temprana edad. La infertilidad por otro lado es más frecuente en personas mayores de 35 años. La combinación de un índice de masa corporal elevado e infertilidad ocasiona que las personas que consultan por infertilidad presenten un panorama menos favorable. Los factores causales de infertilidad femenina pueden verse afectados por la asociación de un índice de masa corporal elevado, por lo tanto, el objetivo principal de esta investigación es identificar los factores causales de infertilidad femenina que presentaron mujeres que utilizaron técnicas de reproducción asistida y que presentaron un índice de masa corporal elevado. Para esto se llevó a cabo una investigación descriptiva de tipo transversal utilizando una metodología cuantitativa. Los hallazgos se realizaron mediante la revisión documental de expedientes clínicos del Centro de Reproducción Humana, CER, Guatemala, en donde se realizó el llenado de un instrumento de recolección de datos el cual posteriormente fue analizado por medio de estadística descriptiva.Fue posible identificar siete factores causales de infertilidad femenina, los cuales corresponden a los factores ovárico, tubárico, uterino, hormonal, peritoneal, cervical y ambiental. Se encontraron casos en los que no fue posible identificar un factor específico. El factor más frecuente es el factor ovárico. Las pacientes menores de 34 años presentan mayor frecuencia de síndrome de ovario poliquístico y obstrucción tubárica mientras que las mayores de 35 años presentan la baja reserva ovárica y la realización de esterilización tubárica como principales causas de infertilidad. El sobrepeso estuvo presente en mayor frecuencia en todos los factores encontrados. La técnica de reproducción asistida más utilizada fue la fertilización in vitro, seguida de la inseminación intrauterina. Se concluye, por lo tanto, que el factor ovárico es el principal factor causal de infertilidad en la mujer guatemalteca con obesidad y con sobrepeso, la obstrucción tubárica es el segundo más frecuente y la miomatosis uterina el tercero. Los factores ambiental y cervical se encontraron en combinación en todas las ocasiones.
| Tipo de Documento: | Tesis (Masters) |
|---|---|
| Palabras Clave: | Infertilidad femenina, Factores de infertilidad, Reserva ovárica, Técnicas de reproducción asistida, Índice de masa corporal |
| Clasificación temática: | Materias > Biomedicina |
| Divisiones: | Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster |
| Depositado: | 17 Nov 2023 23:30 |
| Ultima Modificación: | 17 Nov 2023 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/2305 |
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Introduction Cancer in older adults is often associated with functional limitations, geriatric syndromes, poor self-rated health, vulnerability, and frailty, and these conditions might worsen treatment-related side effects. Recent guidelines for patients with cancer during and after treatment have documented the beneficial effects of exercise to counteract certain side effects; however, little is known about the role of exercise during cancer treatment in older adults. Materials and Methods This is a multicentre randomised controlled trial in which 200 participants will be allocated to a control group or an intervention group (the sample size has been calculated to detect a clinical difference of 1 point in Short Physical Performance Battery (SPPB) score, assuming an α error of 0.05, a β error of 0.20, and a 10 % loss rate). Patients aged ≥70 years, diagnosed with any type of solid cancer and candidates for systemic treatment are eligible. Subjects in the intervention group are invited to participate in a 12-week supervised multicomponent exercise programme in addition to receiving usual care. Study assessments are conducted at baseline and three months. The primary outcome measure is physical function as assessed by the SPPB. Secondary outcome measures include comprehensive geriatric assessment scores (including social situation, basic and instrumental activities of daily living, cognitive function, depression, nutritional status, polypharmacy, geriatric syndromes, pain, and emotional distress), anthropometric characteristics, frailty status, physical fitness, physical activity, cognitive function, quality of life, fatigue, and nutritional status. Study assessments also include analysis of inflammatory, endocrine, and nutritional mediators in serum and plasma as potential frailty biomarkers at mRNA and protein levels and multiparametric flow cytometric analysis to measure immunosenescence markers on T and NK cells. Discussion This study seeks to extend our knowledge on exercise interventions during systemic anticancer treatment in patients over 70 years of age. Results from this research will guide the management of older adults during systemic treatment in hospitals seeking to enhance the standard of care.
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