As Franquias e suas forças no empreendedorismo, e as Financeiras de Crédito como opção de negócio.
Tesis
Materias > Comunicación
Materias > Educación
Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster
Cerrado
Portugués
O Empreendedorismo oferece graus elevados de realização pessoal, somado com sonhos e impulsionados pelo desejo de uma estabilidade financeira diferente do cenário de crise resultante de desempregos ocasionados pela pandemia covid-19. Recentemente os acessos ao empreendedorismo têm se tornado ainda mais crescente pelas habilidades e competências motivados em diversos perfis para ser dono do próprio negócio, seja pela necessidade ou oportunidade. Sabe-se que o empreendedorismo também caminha paralelamente a muitos desses sonhos seja em dirigir um negócio próprio independente ou até mesmo operar um negócio já consolidado chamado de Franquia existente no mercado com um modelo de operação formatado e comprovado com sua performance empresarial. Este estudo tem por objetivo analisar a influência e a força do empreendedorismo de franchising no Brasil comparado ao mercado de empreendedorismo negócio próprio independente. Analisando o material em estudo, o mercado de franquias apresenta um plano completo estratégico de negócios afim, de assessorar os franqueados, ponto chave diferencial comparado ao empreendimento em negócio independente. O que torna a franquia uma opção de empreendedorismo mais atrativa para investir, de baixo risco e mais chances de sucesso no mercado. Para isso realizou-se investigação qualitativa, pesquisa descritiva de sua natureza básica acompanhado de pesquisa bibliográfica, no objetivo de coleta de dados para apresentar o mercado do franchising comparado a negócio independente. De base aos argumentos analisados, percebe-se que pela clareza de informações e a credibilidade desse mercado de franquias, é uma oportunidade de negócio com investimento acessível e de baixo risco, diversos segmentos para todas classes sociais adentrarem ao empreendimento. Mercado este de franquias, atrativo pela rede de assessoria contínua ao franqueado com bons índices de sobrevivência no mercado.
metadata
Medianeira dos Santos Gonçalves, Andreia
mail
andreia_marketing@hotmail.com
(2022)
As Franquias e suas forças no empreendedorismo, e as Financeiras de Crédito como opção de negócio.
Masters thesis, SIN ESPECIFICAR.
Resumen
O Empreendedorismo oferece graus elevados de realização pessoal, somado com sonhos e impulsionados pelo desejo de uma estabilidade financeira diferente do cenário de crise resultante de desempregos ocasionados pela pandemia covid-19. Recentemente os acessos ao empreendedorismo têm se tornado ainda mais crescente pelas habilidades e competências motivados em diversos perfis para ser dono do próprio negócio, seja pela necessidade ou oportunidade. Sabe-se que o empreendedorismo também caminha paralelamente a muitos desses sonhos seja em dirigir um negócio próprio independente ou até mesmo operar um negócio já consolidado chamado de Franquia existente no mercado com um modelo de operação formatado e comprovado com sua performance empresarial. Este estudo tem por objetivo analisar a influência e a força do empreendedorismo de franchising no Brasil comparado ao mercado de empreendedorismo negócio próprio independente. Analisando o material em estudo, o mercado de franquias apresenta um plano completo estratégico de negócios afim, de assessorar os franqueados, ponto chave diferencial comparado ao empreendimento em negócio independente. O que torna a franquia uma opção de empreendedorismo mais atrativa para investir, de baixo risco e mais chances de sucesso no mercado. Para isso realizou-se investigação qualitativa, pesquisa descritiva de sua natureza básica acompanhado de pesquisa bibliográfica, no objetivo de coleta de dados para apresentar o mercado do franchising comparado a negócio independente. De base aos argumentos analisados, percebe-se que pela clareza de informações e a credibilidade desse mercado de franquias, é uma oportunidade de negócio com investimento acessível e de baixo risco, diversos segmentos para todas classes sociais adentrarem ao empreendimento. Mercado este de franquias, atrativo pela rede de assessoria contínua ao franqueado com bons índices de sobrevivência no mercado.
| Tipo de Documento: | Tesis (Masters) |
|---|---|
| Palabras Clave: | Franquia, Franchise, Empreendedorismo, Crédito, Financeira |
| Clasificación temática: | Materias > Comunicación Materias > Educación |
| Divisiones: | Universidad Europea del Atlántico > Docencia > Trabajos finales de Máster |
| Depositado: | 03 Nov 2023 23:30 |
| Ultima Modificación: | 03 Nov 2023 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/1649 |
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Background Post-kala-azar dermal leishmaniasis (PKDL) is a skin condition that can become a complication in about 15 % of patients who have had kala-azar. Despite its significance, treatment options for PKDL are still limited. This systematic review and meta-analysis aim to evaluate the efficacy of amphotericin B for this condition. Methods PubMed, Embase, Cochrane, and Web of Science databases were searched for randomized controlled trials (RCTs) that reported the efficacy of Liposomal Amphotericin B in the treatment of PKDL. This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Events per 100 observations with 95 % confidence intervals were performed for outcomes. Results Nine studies with 639 patients were included, the treatment durations ranging from 7 to 60 days. The mean age ranged from 9.2 to 31.0 years, and 359 patients were male. The PKDL treatment with liposomal amphotericin B resulted in a cure rate of 91.36 % (95 % CI: 76.60-97.15). However, a relapse was observed in 11.42 % (95 % CI: 6.20-20.8) of patients. Adverse events were common, with hepatic enzyme elevation (ALT/AST) being the most frequent (61.75 %; 95 % CI: 21.81–90.33), followed by fever in 29.93 % of cases (95 % CI: 5.09–77.30). Among the more serious side effects, decreased serum potassium was observed in 19.27 % (95 % CI: 3.84–58.82), and increased serum creatinine, indicative of nephrotoxicity, occurred in 15.08 % (95 % CI: 3.97–43.27). Nausea or vomiting, although less severe, affected 12.36 % of patients (95 % CI: 4.81–28.25). Conclusions These findings highlight that while liposomal amphotericin B is a potent therapeutic option for PKDL, its administration requires careful management and clinical vigilance to optimize outcomes and minimize risks.
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Understanding how dietary compounds affect human health is challenged by their molecular complexity and cell-type–specific effects. Conventional multi-cell type (bulk) analyses obscure cellular heterogeneity, while animal and standard in vitro models often fail to replicate human physiology. Single-cell omics technologies—such as single-cell RNA sequencing, as well as single-cell–resolved proteomic and metabolomic approaches—enable high-resolution investigation of nutrient–cell interactions and reveal mechanisms at a single-cell resolution. When combined with advanced human-derived in vitro systems like organoids and organ-on-chip platforms, they support mechanistic studies in physiologically relevant contexts. This review outlines emerging applications of single-cell omics in nutrition research, emphasizing their potential to uncover cell-specific dietary responses, identify nutrient-sensitive pathways, and capture interindividual variability. It also discusses key challenges—including technical limitations, model selection, and institutional biases—and identifies strategic directions to facilitate broader adoption in the field. Collectively, single-cell omics offer a transformative framework to advance human-centric nutrition research.
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