Fish consumption, cognitive impairment and dementia: an updated dose-response meta-analysis of observational studies
Artículo
Materias > Biomedicina
Materias > Alimentación
Universidad Europea del Atlántico > Investigación > Artículos y libros
Abierto
Inglés
Background
Cognitive impairment is projected to affect a preponderant proportion of the aging population. Lifelong dietary habits have been hypothesized to play a role in preventing cognitive decline. Among the most studied dietary components, fish consumptionhas been extensively studied for its potential effects on the human brain.
Aims
To perform a meta-analysis of observational studies exploring the association between fish intake and cognitive impairment/decline and all types of dementia.
Methods
A systematic search of electronic databases was performed to identify observational studies providing quantitative data on fish consumption and outcomes of interest. Random effects models for meta-analyses using only extreme exposure categories, subgroup analyses, and dose-response analyses were performed to estimate cumulative risk ratios (RRs) and 95% confidence intervals (CIs).
Results
The meta-analysis comprised 35 studies. Individuals reporting the highest vs. the lowest fish consumption were associated with a lower likelihood of cognitive impairment/decline (RR = 0.82, 95% CI: 0.75, 0.90, I2 = 61.1%), dementia (RR = 0.82, 95% CI: 0.73, 0.93, I2 = 38.7%), and Alzheimer’s disease (RR = 0.80, 95% CI: 0.67, 0.96, I2 = 20.3%). The dose-response relation revealed a significantly decreased risk of cognitive impairment/decline and all cognitive outcomes across higher levels of fish intake up to 30% for 150 g/d (RR = 0.70, 95% CI: 0.52, 0.95). The results of this relation based on APOE ε4 allele status was mixed based on the outcome investigated.
Conclusions
Current findings suggest fish consumption is associated with a lower risk of cognitive impairment/decline in a dose-response manner, while for dementia and Alzheimer’s disease there is a need for further studies to improve the strength of evidence.
metadata
Godos, Justyna; Micek, Agnieszka; Currenti, Walter; Franchi, Carlotta; Poli, Andrea; Battino, Maurizio; Dolci, Alberto; Ricci, Cristian; Ungvari, Zoltan y Grosso, Giuseppe
mail
SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR
(2024)
Fish consumption, cognitive impairment and dementia: an updated dose-response meta-analysis of observational studies.
Aging Clinical and Experimental Research, 36 (1).
ISSN 1720-8319
|
Texto
s40520-024-02823-6.pdf Descargar (1MB) | Vista Previa |
Resumen
Background Cognitive impairment is projected to affect a preponderant proportion of the aging population. Lifelong dietary habits have been hypothesized to play a role in preventing cognitive decline. Among the most studied dietary components, fish consumptionhas been extensively studied for its potential effects on the human brain. Aims To perform a meta-analysis of observational studies exploring the association between fish intake and cognitive impairment/decline and all types of dementia. Methods A systematic search of electronic databases was performed to identify observational studies providing quantitative data on fish consumption and outcomes of interest. Random effects models for meta-analyses using only extreme exposure categories, subgroup analyses, and dose-response analyses were performed to estimate cumulative risk ratios (RRs) and 95% confidence intervals (CIs). Results The meta-analysis comprised 35 studies. Individuals reporting the highest vs. the lowest fish consumption were associated with a lower likelihood of cognitive impairment/decline (RR = 0.82, 95% CI: 0.75, 0.90, I2 = 61.1%), dementia (RR = 0.82, 95% CI: 0.73, 0.93, I2 = 38.7%), and Alzheimer’s disease (RR = 0.80, 95% CI: 0.67, 0.96, I2 = 20.3%). The dose-response relation revealed a significantly decreased risk of cognitive impairment/decline and all cognitive outcomes across higher levels of fish intake up to 30% for 150 g/d (RR = 0.70, 95% CI: 0.52, 0.95). The results of this relation based on APOE ε4 allele status was mixed based on the outcome investigated. Conclusions Current findings suggest fish consumption is associated with a lower risk of cognitive impairment/decline in a dose-response manner, while for dementia and Alzheimer’s disease there is a need for further studies to improve the strength of evidence.
| Tipo de Documento: | Artículo |
|---|---|
| Palabras Clave: | Fish; Dementia; Cognitive status; Alzheimer’s disease; Meta-analysis |
| Clasificación temática: | Materias > Biomedicina Materias > Alimentación |
| Divisiones: | Universidad Europea del Atlántico > Investigación > Artículos y libros |
| Depositado: | 23 Sep 2024 23:30 |
| Ultima Modificación: | 23 Sep 2024 23:30 |
| URI: | https://repositorio.uneatlantico.es/id/eprint/14336 |
Acciones (logins necesarios)
 |
Ver Objeto |
<a href="/10290/1/Influence%20of%20E-learning%20training%20on%20the%20acquisition%20of%20competences%20in%20basketball%20coaches%20in%20Cantabria.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/10290/1.hassmallThumbnailVersion/Influence%20of%20E-learning%20training%20on%20the%20acquisition%20of%20competences%20in%20basketball%20coaches%20in%20Cantabria.pdf" border="0"/></a>
en
open
The main aim of this study was to analyse the influence of e-learning training on the acquisition of competences in basketball coaches in Cantabria. The current landscape of basketball coach training shows an increasing demand for innovative training models and emerging pedagogies, including e-learning-based methodologies. The study sample consisted of fifty students from these courses, all above 16 years of age (36 males, 14 females). Among them, 16% resided outside the autonomous community of Cantabria, 10% resided more than 50 km from the city of Santander, 36% between 10 and 50 km, 14% less than 10 km, and 24% resided within Santander city. Data were collected through a Google Forms survey distributed by the Cantabrian Basketball Federation to training course students. Participation was voluntary and anonymous. The survey, consisting of 56 questions, was validated by two sports and health doctors and two senior basketball coaches. The collected data were processed and analysed using Microsoft® Excel version 16.74, and the results were expressed in percentages. The analysis revealed that 24.60% of the students trained through the e-learning methodology considered themselves fully qualified as basketball coaches, contrasting with 10.98% of those trained via traditional face-to-face methodology. The results of the study provide insights into important characteristics that can be adjusted and improved within the investigated educational process. Moreover, the study concludes that e-learning training effectively qualifies basketball coaches in Cantabria.
Josep Alemany Iturriaga mail josep.alemany@uneatlantico.es, Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Javier Jorge mail , Kamil Giglio mail ,
Alemany Iturriaga
en
close
Technological firms invest in R&D looking for innovative solutions but assuming high costs and great (technological) uncertainty regarding final results and returns. Additionally, they face other problems related to R&D management. This empirical study tries to determine which of the factors favour or constrain the decision of these firms to engage in R&D. The analysis uses financial data of 14,619 ICT listed companies of 22 countries from 2003 to 2018. Additionally, macroeconomic data specific for the countries and the sector were used. For the analysis of dynamic panel data, a System-GMM method is used. Among the findings, we highlight that cash flow, contrary to the known theoretical models and empirical evidences, negatively impacts on R&D investment. Debt is neither the right source for R&D funding, as the effect is also negative. This suggests that ICT companies are forced to manage their R&D activities differently, relying more on other funding sources, taking advantage of growth opportunities and benefiting from a favourable macroeconomic environment in terms of growth and increased business sector spending on R&D. These results are similar in both sub-sectors and in all countries, both bank- and market based. The exception is firms with few growth opportunities and little debt.
Inna Alexeeva-Alexeev mail inna.alexeeva@uneatlantico.es, Cristina Mazas Pérez-Oleag mail cristina.mazas@uneatlantico.es,
Alexeeva-Alexeev
en
open
Assessment Of Lower Limb Asymmetries In Soccer Players According To The Stage Of The Season
PURPOSE: Muscle asymmetries can be associated with increased risk of injury. Using countermovement jump (CMJ) to analyze muscular asymmetries in the lower limbs of soccer players, according to the stage of the season.
Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Jeffrey Mjaanes mail , Angel Olider Rojas Vistorte mail , Julio Calleja-González mail ,
Velarde-Sotres
<a href="/14206/1/mnm_2024_17-3_mnm-17-3-mnm240038_mnm-17-mnm240038.pdf" class="ep_document_link"><img class="ep_doc_icon" alt="[img]" src="/14206/1.hassmallThumbnailVersion/mnm_2024_17-3_mnm-17-3-mnm240038_mnm-17-mnm240038.pdf" border="0"/></a>
en
open
Exploring body composition and somatotype profiles among youth professional soccer players
OBJECTIVE: This study aimed to analyze the body composition and somatotype of professional soccer players, investigating variations across categories and playing positions. METHODS: An observational, cross-sectional, and analytical study was conducted with 51 male professional soccer players in the U-19 and U-20 categories. Data about sex, age, height, and weight were collected between March and May 2023. Body composition analysis utilized the ISAK protocol for the restricted profile, while somatotype categorization employed the Heath and Carter formula. Statistical analysis was performed using IBM SPSS Statistics V.26, which involved the application of Mann-Whitney and Kruskal-Wallis tests to discern differences in body composition variables and proportionality based on categories and playing positions. The Dunn test further identified specific positions exhibiting significant differences. RESULTS: The study encompassed 51 players, highlighting meaningful differences in body composition. The average body mass in kg was 75.8 (±6.9) for U-20 players and 70.5 (±6.1) for U-19 players. The somatotype values were 2.6-4.6-2.3 for U-20 players and 2.5-4.3-2.8 for U-19 players, with a predominance of muscle mass in all categories, characterizing them as balanced mesomorphs. CONCLUSIONS: Body composition and somatotype findings underscore distinctions in body mass across categories and playing positions, with notably higher body mass and muscle mass predominance in elevated categories. However, the prevailing skeletal muscle development establishes a significant semblance with the recognized somatotype standard for soccer.
Raynier Zambrano-Villacres mail , Evelyn Frias-Toral mail , Emily Maldonado-Ponce mail , Carlos Poveda-Loor mail , Paola Leal mail , Álvaro Velarde-Sotres mail alvaro.velarde@uneatlantico.es, Alice Leonardi mail , Bruno Trovato mail , Federico Roggio mail , Alessandro Castorina mail , Xu Wenxin mail , Giuseppe Musumeci mail ,
Zambrano-Villacres
en
open
Aging, age-related diseases, oxidative stress and plant polyphenols: Is this a true relationship?
Aging is a physiological process characterized by a progressive deterioration of all the biological functions and a marked reduction in stress resistance, thus resulting in an increased susceptibility to several pathologies
Manuela Cassotta mail manucassotta@gmail.com, José L. Quiles mail jose.quiles@uneatlantico.es, Francesca Giampieri mail francesca.giampieri@uneatlantico.es, Maurizio Battino mail maurizio.battino@uneatlantico.es,
Cassotta