TY  - JOUR
JF  - Journal of the Science of Food and Agriculture
N2  - Berries are a relevant source of micronutrients and nonessential phytochemicals, such as polyphenol compounds, that play a synergistic and cumulative role in human health promotion. Several systematic analyses showed that berry phenolics are able to detoxify reactive oxygen and nitrogen species, blocking their production, to intervene in the cell cycle, participating in the transduction and expression of genes involved in apoptosis, and to repair oxidative DNA damage. As a consequence, the improvement of the nutritional quality of berries has become a new quality target of breeding and biotechnological strategies, to control or to increase the content of specific health-related compounds in fruits. This work reviews, on the basis of the in vitro and in vivo evidence, the main berries' phytochemical compounds and their possible mechanisms of action on pathways involved in several type of diseases, with particular attention to cancer, inflammation, neurodegeneration, diabetes and cardiovascular diseases. © 2015 Society of Chemical Industry
Y1  - 2015///
IS  - 2
SP  - 365
VL  - 96
SN  - 00225142
UR  - http://doi.org/10.1002/jsfa.7216
ID  - uneatlantico94
EP  - 371
TI  - The genetic aspects of berries: from field to health
AV  - none
A1  - Mazzoni, Luca
A1  - Perez-Lopez, Patricia
A1  - Giampieri, Francesca
A1  - Alvarez-Suarez, José M.
A1  - Gasparrini, Massimiliano
A1  - Forbes-Hernandez, Tamara Y.
A1  - Quiles, José L.
A1  - Mezzetti, Bruno
A1  - Battino, Maurizio
KW  - Berries; Bioactive compounds; Genetic improvement; Cancer; Inflammation; Neurological diseases.
ER  -