TY - JOUR Y1 - 2016/00/00/ JF - Journal of Agricultural and Food Chemistry N2 - The potential health benefits associated with dietary intake of fruits have attracted increasing interest. Among berries, the strawberry is a rich source of several nutritive and non-nutritive bioactive compounds, which are implicated in various health-promoting and disease preventive effects. A plethora of studies have examined the benefits of strawberry consumption, such as prevention of inflammation disorders and oxidative stress, reduction of obesity related disorders and heart disease risk, and protection against various types of cancer. This review provides an overview of their nutritional and non-nutritional bioactive compounds and which factors affect their content in strawberries. In addition, the bioavailability and metabolism of major strawberry phytochemicals as well as their actions in combating many pathologies, including cancer, metabolic syndrome, cardiovascular disease, obesity, diabetes, neurodegeneration, along with microbial pathogenesis have been reviewed, with a particular attention to human studies. SP - 4435 IS - 22 VL - 64 UR - http://doi.org/10.1021/acs.jafc.6b00857 SN - 0021-8561 TI - Promising Health Benefits of the Strawberry: A Focus on Clinical Studies EP - 4449 ID - uneatlantico91 AV - none A1 - Afrin, Sadia A1 - Gasparrini, Massimiliano A1 - Forbes-Hernandez, Tamara Y. A1 - Reboredo-Rodriguez, Patricia A1 - Mezzetti, Bruno A1 - Varela-López, Alfonso A1 - Giampieri, Francesca A1 - Battino, Maurizio KW - Strawberry; Phenolic compounds; Anti-inflammation; Cardioprotection; Antimetabolic syndrome; Antidiabetes; Anticancer; Neuroprotection. ER -