@article{uneatlantico85,
            year = {2018},
           title = {Intracellular signaling pathways of inflammation modulated by dietary flavonoids: The most recent evidence},
         journal = {Critical Reviews in Food Science and Nutrition},
          number = {17},
           month = {Sin especificar},
           pages = {2908--2924},
          author = {Lei Chen and Hui Teng and Zhen Jia and Maurizio Battino and Anca Miron and Zhiling Yu and Hui Cao and Jianbo Xiao},
          volume = {58},
        abstract = {Dietary flavonoids, which occur in many plant foods, are considered as the most active constituents among the plant-derived ones in vitro and in vivo. To date, many studies have addressed the anti-inflammatory activity of flavonoids. However, their considerable structural diversity and in vivo bioavailability make them able to modulate different signaling pathways. The present review attempted to summarize and highlight a broad range of inflammation-associated signaling pathways modulated by flavonoids. Finally, based on the current scientist's literature, structure-activity relationships were concluded. Dietary flavonoids have the ability to attenuate inflammation by targeting different intracellular signaling pathways triggered by NF-{\ensuremath{\kappa}}B, AP-1, PPAR, Nrf2, and MAPKs. Identification of the main structural features required for the modulation of these inflammation-related pathways (hydroxylation pattern, C2=C3 double bond) have an important role to play in the development of new anti-inflammatory drugs.},
             url = {http://repositorio.uneatlantico.es/id/eprint/85/},
        keywords = {Flavonoids; Inflammation; Intracellular signaling pathways; Strectyre-activity relationship.}
}