…
comment: The repository administrator has not yet configured an RDF license.
primary topic: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells
type: AcademicArticle
type: Article
abstract: Leiomyosarcoma is an aggressive soft tissue sarcoma derived from the smooth muscle cells of the uterus. We tested the effect of Romina strawberry extract treatment on three-dimensional cultured uterine leiomyosarcoma cells. We established 3D cultures in agarose gel, where the cells seeded were able to form spheroids. We performed the observation and counting of the spheroids with a phase-contrast optical microscope, finding a decrease in the number of spheroids formed in the plates after 24 and 48 h treatment with 250 µg/mL of cultivar Romina strawberry extract. We also characterized the spheroids morphology by DNA binding fluorescent-stain observation, hematoxylin and eosin stain, and Masson’s trichrome stain. Finally, the real-time PCR showed a reduced expression of extracellular matrix genes after strawberry treatment. Overall, our data suggest that the fruit extract of this strawberry cultivar may be a useful therapeutic adjuvant for the management of uterine leiomyosarcoma.
date: 2023-05
volume: 15
issue: 11
is part of: Nutrients
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has document: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
subject: Nutrition

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
type: Document
has file: nutrients-15-02557.pdf
has part: nutrients-15-02557.pdf

Nutrients
type: Collection
issn: 20726643

Francesca Giampieri
type: Person
given name: Francesca
family name: Giampieri

Maurizio Battino
type: Person
given name: Maurizio
family name: Battino

Stefano Raffaele Giannubilo
type: Person
given name: Stefano Raffaele
family name: Giannubilo

Andrea Ciavattini
type: Person
given name: Andrea
family name: Ciavattini

Giovanni Delli Carpini
type: Person
given name: Giovanni
family name: Delli Carpini

Franco Capocasa
type: Person
given name: Franco
family name: Capocasa

Stefania Greco
type: Person
given name: Stefania
family name: Greco

Pamela Pellegrino
type: Person
given name: Pamela
family name: Pellegrino

Bruno Mezzetti
type: Person
given name: Bruno
family name: Mezzetti

Pasquapina Ciarmela
type: Person
given name: Pasquapina
family name: Ciarmela

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
type: Document
is version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is volatile version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is index codes version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has file: indexcodes.txt
has part: indexcodes.txt

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
type: Document
is version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is volatile version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
islightbox thumbnail version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has file: lightbox.jpg
has part: lightbox.jpg

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
type: Document
is version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is volatile version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
ispreview thumbnail version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has file: preview.jpg
has part: preview.jpg

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
type: Document
is version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is volatile version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
ismedium thumbnail version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has file: medium.jpg
has part: medium.jpg

The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Otro)
type: Document
is version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
is volatile version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
issmall thumbnail version of: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells (Texto)
has file: small.jpg
has part: small.jpg

HTML Summary of #7353 The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells
format: text/html
primary topic: The In Vitro Effects of Romina Strawberry Extract on 3D Uterine Leiomyosarcoma Cells

Nutrition
type: Concept
preferred label: Alimentación @es