eprintid: 6511 rev_number: 8 eprint_status: archive userid: 2 dir: disk0/00/00/65/11 datestamp: 2023-03-24 23:30:11 lastmod: 2023-03-24 23:30:13 status_changed: 2023-03-24 23:30:11 type: article metadata_visibility: show creators_name: Portes, Juliana creators_name: Bullón, Beatriz creators_name: Gallardo, Isabel creators_name: Fernandez-Riejos, Patricia creators_name: Quiles, José Luis creators_name: Giampieri, Francesca creators_name: Bullón, Pedro creators_id: creators_id: creators_id: creators_id: creators_id: creators_id: francesca.giampieri@uneatlantico.es creators_id: title: Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals ispublished: pub subjects: uneat_bm divisions: uneatlantico_produccion_cientifica full_text_status: public keywords: Periodontitis; Type 2 diabetes mellitus; Prediabetes; Lifestyle; Western diet; Physical activity abstract: Objective The prevalence of undiagnosed diabetes was estimated to increase with age and can reach 3.5%. The purpose of the study was to evaluate the prevalence of undiagnosed diabetes and prediabetes in the elderly patients who attended a dental clinic and to find common risk factors. Methods Male patients, older than 50 years, attended their first dental visit to the School of Dentistry for a period of two years, and it was proposed to evaluate undiagnosed type 2 diabetes mellitus. Periodontal, biochemical, microbiological examinations, nutritional profile, and physical activity were performed. Results A total of 106 patients were examined, 6 (5.6%) had diabetes, and 37 (34.9%) had prediabetes without prior diagnosis. The severity of periodontitis was greater in patients with diabetes. Most of the patients were overweight and had increased systolic blood pressure. Patients with prediabetes and periodontitis had a low adherence to the Mediterranean diet. Tannerella forsythia was present in more patients with periodontitis, and the prevalence of Aggregatibacter actinomycetemcomitans is practically absent in groups with periodontitis, except for the group with diabetes. Conclusions In the population studied, the prevalence of patients without a diagnosis of diabetes and prediabetes was very high and underestimated. The increased severity of periodontitis in patients with diabetes and in conjunction with the high level of cortisol seen in patients with periodontitis, especially those with diabetes, emphasize the dysregulation of the immunoinflammatory system. date: 2023 publication: Journal of Dentistry volume: 132 pagerange: 104480 id_number: doi:10.1016/j.jdent.2023.104480 refereed: TRUE issn: 03005712 official_url: http://doi.org/10.1016/j.jdent.2023.104480 access: open language: en citation: Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica Abierto Inglés Objective The prevalence of undiagnosed diabetes was estimated to increase with age and can reach 3.5%. The purpose of the study was to evaluate the prevalence of undiagnosed diabetes and prediabetes in the elderly patients who attended a dental clinic and to find common risk factors. Methods Male patients, older than 50 years, attended their first dental visit to the School of Dentistry for a period of two years, and it was proposed to evaluate undiagnosed type 2 diabetes mellitus. Periodontal, biochemical, microbiological examinations, nutritional profile, and physical activity were performed. Results A total of 106 patients were examined, 6 (5.6%) had diabetes, and 37 (34.9%) had prediabetes without prior diagnosis. The severity of periodontitis was greater in patients with diabetes. Most of the patients were overweight and had increased systolic blood pressure. Patients with prediabetes and periodontitis had a low adherence to the Mediterranean diet. Tannerella forsythia was present in more patients with periodontitis, and the prevalence of Aggregatibacter actinomycetemcomitans is practically absent in groups with periodontitis, except for the group with diabetes. Conclusions In the population studied, the prevalence of patients without a diagnosis of diabetes and prediabetes was very high and underestimated. The increased severity of periodontitis in patients with diabetes and in conjunction with the high level of cortisol seen in patients with periodontitis, especially those with diabetes, emphasize the dysregulation of the immunoinflammatory system. metadata Portes, Juliana; Bullón, Beatriz; Gallardo, Isabel; Fernandez-Riejos, Patricia; Quiles, José Luis; Giampieri, Francesca y Bullón, Pedro mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR (2023) Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals. Journal of Dentistry, 132. p. 104480. ISSN 03005712 document_url: http://repositorio.uneatlantico.es/id/eprint/6511/1/1-s2.0-S0300571223000672-main.pdf