TY - JOUR AV - public A1 - Portes, Juliana A1 - Bullón, Beatriz A1 - Gallardo, Isabel A1 - Fernandez-Riejos, Patricia A1 - Quiles, José Luis A1 - Giampieri, Francesca A1 - Bullón, Pedro KW - Periodontitis; Type 2 diabetes mellitus; Prediabetes; Lifestyle; Western diet; Physical activity ID - uneatlantico6511 TI - Prevalence of undiagnosed diabetes and prediabetes related to periodontitis and its risk factors in elderly individuals VL - 132 UR - http://doi.org/10.1016/j.jdent.2023.104480 SN - 03005712 N2 - Objective The prevalence of undiagnosed diabetes was estimated to increase with age and can reach 3.5%. The purpose of the study was to evaluate the prevalence of undiagnosed diabetes and prediabetes in the elderly patients who attended a dental clinic and to find common risk factors. Methods Male patients, older than 50 years, attended their first dental visit to the School of Dentistry for a period of two years, and it was proposed to evaluate undiagnosed type 2 diabetes mellitus. Periodontal, biochemical, microbiological examinations, nutritional profile, and physical activity were performed. Results A total of 106 patients were examined, 6 (5.6%) had diabetes, and 37 (34.9%) had prediabetes without prior diagnosis. The severity of periodontitis was greater in patients with diabetes. Most of the patients were overweight and had increased systolic blood pressure. Patients with prediabetes and periodontitis had a low adherence to the Mediterranean diet. Tannerella forsythia was present in more patients with periodontitis, and the prevalence of Aggregatibacter actinomycetemcomitans is practically absent in groups with periodontitis, except for the group with diabetes. Conclusions In the population studied, the prevalence of patients without a diagnosis of diabetes and prediabetes was very high and underestimated. The increased severity of periodontitis in patients with diabetes and in conjunction with the high level of cortisol seen in patients with periodontitis, especially those with diabetes, emphasize the dysregulation of the immunoinflammatory system. JF - Journal of Dentistry Y1 - 2023/// ER -