eprintid: 6448 rev_number: 8 eprint_status: archive userid: 2 dir: disk0/00/00/64/48 datestamp: 2023-03-20 23:30:10 lastmod: 2023-03-20 23:30:12 status_changed: 2023-03-20 23:30:10 type: article metadata_visibility: show creators_name: Beltrán-Noboa, Andrea creators_name: Jordan-Álvarez, Alejandro creators_name: Guevara-Terán, Mabel creators_name: Gallo, Blanca creators_name: Berrueta, Luis A. creators_name: Giampieri, Francesca creators_name: Battino, Maurizio creators_name: Álvarez-Suarez, José M. creators_name: Tejera, Eduardo creators_id: creators_id: creators_id: creators_id: creators_id: creators_id: francesca.giampieri@uneatlantico.es creators_id: maurizio.battino@uneatlantico.es creators_id: creators_id: title: Exploring the Chemistry of Ocimum Species under Specific Extractions and Chromatographic Methods: A Systematic Review ispublished: pub subjects: uneat_sn divisions: uneatlantico_produccion_cientifica full_text_status: public keywords: Chemical composition, Extraction, Mathematical methods, Molecules, Organic acids abstract: Ocimum is considered the largest genus in the Lamiacea family. The genus includes basil, a group of aromatic plants with a wide range of culinary uses that nowadays draws attention for its medicinal and pharmaceutical potential. This systematic review intends to explore the chemical composition of nonessential oils and their variation across different Ocimum species. Moreover, we aimed to identify the state of knowledge regarding the molecular space in this genus as well as the different methods of extraction/identification and geographical location. Seventy-nine eligible articles were selected for the final analysis, from which we extracted more than 300 molecules. We found that the countries with the highest number of studies into Ocimum species are India, Nigeria, Brazil, and Egypt. However, from all known species of Ocimum, only 12 were found to have an extensive chemical characterization, particularly Ocimum basilicum and Ocimum tenuiflorum. Our study focused especially on alcoholic, hydroalcoholic, and water extracts, in which the main techniques for compound identifications are GC-MS, LC-MS, and LC-UV. Across the compiled molecules, we found a wide variety of compounds, especially flavonoids, phenolic acids, and terpenoids, suggesting that this genus could be a very useful source of possible bioactive compounds. The information collected in this review also emphasizes the huge gap between the vast number of Ocimum species discovered and the number of studies in each of them that determined the chemical characterization. date: 2023 publication: ACS Omega id_number: doi:10.1021/acsomega.3c00043 refereed: TRUE issn: 2470-1343 official_url: http://doi.org/10.1021/acsomega.3c00043 access: open language: en citation: Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica Abierto Inglés Ocimum is considered the largest genus in the Lamiacea family. The genus includes basil, a group of aromatic plants with a wide range of culinary uses that nowadays draws attention for its medicinal and pharmaceutical potential. This systematic review intends to explore the chemical composition of nonessential oils and their variation across different Ocimum species. Moreover, we aimed to identify the state of knowledge regarding the molecular space in this genus as well as the different methods of extraction/identification and geographical location. Seventy-nine eligible articles were selected for the final analysis, from which we extracted more than 300 molecules. We found that the countries with the highest number of studies into Ocimum species are India, Nigeria, Brazil, and Egypt. However, from all known species of Ocimum, only 12 were found to have an extensive chemical characterization, particularly Ocimum basilicum and Ocimum tenuiflorum. Our study focused especially on alcoholic, hydroalcoholic, and water extracts, in which the main techniques for compound identifications are GC-MS, LC-MS, and LC-UV. Across the compiled molecules, we found a wide variety of compounds, especially flavonoids, phenolic acids, and terpenoids, suggesting that this genus could be a very useful source of possible bioactive compounds. The information collected in this review also emphasizes the huge gap between the vast number of Ocimum species discovered and the number of studies in each of them that determined the chemical characterization. metadata Beltrán-Noboa, Andrea; Jordan-Álvarez, Alejandro; Guevara-Terán, Mabel; Gallo, Blanca; Berrueta, Luis A.; Giampieri, Francesca; Battino, Maurizio; Álvarez-Suarez, José M. y Tejera, Eduardo mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2023) Exploring the Chemistry of Ocimum Species under Specific Extractions and Chromatographic Methods: A Systematic Review. ACS Omega. ISSN 2470-1343 document_url: http://repositorio.uneatlantico.es/id/eprint/6448/1/acsomega.3c00043.pdf