<> "The repository administrator has not yet configured an RDF license."^^ . <> . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality"^^ . "Strawberry bioactive compounds are widely known to be powerful antioxidants. In this study, the antioxidant and anti-aging activities of a polyphenol-rich strawberry extract were evaluated using human dermal fibroblasts exposed to H2O2. Firstly, the phenol and flavonoid contents of strawberry extract were studied, as well as the antioxidant capacity. HPLC-DAD analysis was performed to determine the vitamin C and β-carotene concentration, while HPLC-DAD/ESI-MS analysis was used for anthocyanin identification. Strawberry extract presented a high antioxidant capacity, and a relevant concentration of vitamins and phenolics. Pelargonidin- and cyanidin-glycosides were the most representative anthocyanin components of the fruits. Fibroblasts incubated with strawberry extract and stressed with H2O2 showed an increase in cell viability, a smaller intracellular amount of ROS, and a reduction of membrane lipid peroxidation and DNA damage. Strawberry extract was also able to improve mitochondrial functionality, increasing the basal respiration of mitochondria and to promote a regenerative capacity of cells after exposure to pro-oxidant stimuli. These findings confirm that strawberries possess antioxidant properties and provide new insights into the beneficial role of strawberry bioactive compounds on protecting skin from oxidative stress and aging."^^ . "2014" . . . "19" . "6" . . "Molecules"^^ . . . "14203049" . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . "Massimiliano"^^ . "Gasparrini"^^ . "Massimiliano Gasparrini"^^ . . "Maurizio"^^ . "Battino"^^ . "Maurizio Battino"^^ . . "José"^^ . "Alvarez-Suarez"^^ . "José Alvarez-Suarez"^^ . . "Bruno"^^ . "Mezzetti"^^ . "Bruno Mezzetti"^^ . . "Ana"^^ . "Gonzàlez-Paramàs"^^ . "Ana Gonzàlez-Paramàs"^^ . . "Stefano"^^ . "Bompadre"^^ . "Stefano Bompadre"^^ . . "Celestino"^^ . "Santos-Buelga"^^ . "Celestino Santos-Buelga"^^ . . "José"^^ . "Quiles"^^ . "José Quiles"^^ . . "Tamara Y."^^ . "Forbes-Hernandez"^^ . "Tamara Y. Forbes-Hernandez"^^ . . "Luca"^^ . "Mazzoni"^^ . "Luca Mazzoni"^^ . . "Francesca"^^ . "Giampieri"^^ . "Francesca Giampieri"^^ . . . . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Texto)"^^ . . . . . "molecules-19-07798.pdf"^^ . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Otro)"^^ . . . . . . "indexcodes.txt"^^ . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Otro)"^^ . . . . . . "lightbox.jpg"^^ . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Otro)"^^ . . . . . . "preview.jpg"^^ . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Otro)"^^ . . . . . . "medium.jpg"^^ . . . "Polyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality (Otro)"^^ . . . . . . "small.jpg"^^ . . "HTML Summary of #612 \n\nPolyphenol-Rich Strawberry Extract Protects Human Dermal Fibroblasts against Hydrogen Peroxide Oxidative Damage and Improves Mitochondrial Functionality\n\n" . "text/html" . . . "Nutrition"@en . "Alimentación"@es . .