eprintid: 573 rev_number: 6 eprint_status: archive userid: 2 dir: disk0/00/00/05/73 datestamp: 2022-03-16 23:55:04 lastmod: 2022-03-16 23:55:04 status_changed: 2022-03-16 23:55:04 type: article metadata_visibility: show creators_name: Pistollato, Francesca creators_name: Calderón Iglesias, Rubén creators_name: Ruiz Salces, Roberto creators_name: Aparicio-Obregón, Silvia creators_name: Crespo-Álvarez, Jorge creators_name: Dzul Lopez, Luis Alonso creators_name: Manna, Piera Pia creators_name: Giampieri, Francesca creators_name: Battino, Maurizio creators_id: francesca.pistollato@uneatlantico.es creators_id: ruben.calderon@uneatlantico.es creators_id: roberto.ruiz@uneatlantico.es creators_id: silvia.aparicio@uneatlantico.es creators_id: jorge.crespo@uneatlantico.es creators_id: creators_id: creators_id: creators_id: title: Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer’s disease: A focus on human studies ispublished: pub subjects: uneat_bm subjects: uneat_sn divisions: uneatlantico_produccion_cientifica divisions: uninimx_produccion_cientifica full_text_status: none keywords: Dementia; Alzheimer’s disease; Cognitive functions; Nutrient supplementations; Mediterranean diet; DASH diet; MIND diet abstract: Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors and the onset and consolidation of dementia and Alzheimer’s disease (AD). It has been demonstrated that AD, diabetes, obesity, insulin resistance, and cardiovascular disease are strongly interconnected pathologies. Preventive strategies and nutritional interventions seem to be promising approaches to delay neurocognitive decline and reduce the risk of AD and other non-psychiatric co-morbidities. In this regard, healthy dietary patterns, characterized by high intake of plant-based foods, probiotics, antioxidants, soy beans, nuts, and omega-3 polyunsaturated fatty acids, and a low intake of saturated fats, animal-derived proteins, and refined sugars, have been shown to decrease the risk of neurocognitive impairments and eventually the onset of AD. Here we review the role of some nutrients and, in particular, of healthy dietary patterns, such as the Mediterranean diet and other emerging healthy diets, DASH (Dietary Approach to Stop Hypertension) and MIND (Mediterranean-DASH dietIntervention for Neurodegenerative Delay), for the maintenance of cognitive performance, focusing specifically on human studies. The beneficial effects associated with overall diet composition, rather than single nutrient supplementations, for the prevention or the delay of AD and dementia are discussed. date: 2018 publication: Pharmacological Research volume: 131 pagerange: 32-43 id_number: doi:10.1016/j.phrs.2018.03.012 refereed: TRUE issn: 10436618 official_url: http://doi.org/10.1016/j.phrs.2018.03.012 access: close language: en citation: Artículo Materias > Biomedicina Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica Universidad Internacional Iberoamericana México > Investigación > Producción Científica Cerrado Inglés Ample epidemiological evidence suggests a strong correlation among diet, lifestyle factors and the onset and consolidation of dementia and Alzheimer’s disease (AD). It has been demonstrated that AD, diabetes, obesity, insulin resistance, and cardiovascular disease are strongly interconnected pathologies. Preventive strategies and nutritional interventions seem to be promising approaches to delay neurocognitive decline and reduce the risk of AD and other non-psychiatric co-morbidities. In this regard, healthy dietary patterns, characterized by high intake of plant-based foods, probiotics, antioxidants, soy beans, nuts, and omega-3 polyunsaturated fatty acids, and a low intake of saturated fats, animal-derived proteins, and refined sugars, have been shown to decrease the risk of neurocognitive impairments and eventually the onset of AD. Here we review the role of some nutrients and, in particular, of healthy dietary patterns, such as the Mediterranean diet and other emerging healthy diets, DASH (Dietary Approach to Stop Hypertension) and MIND (Mediterranean-DASH dietIntervention for Neurodegenerative Delay), for the maintenance of cognitive performance, focusing specifically on human studies. The beneficial effects associated with overall diet composition, rather than single nutrient supplementations, for the prevention or the delay of AD and dementia are discussed. metadata Pistollato, Francesca; Calderón Iglesias, Rubén; Ruiz Salces, Roberto; Aparicio-Obregón, Silvia; Crespo-Álvarez, Jorge; Dzul Lopez, Luis Alonso; Manna, Piera Pia; Giampieri, Francesca y Battino, Maurizio mail francesca.pistollato@uneatlantico.es, ruben.calderon@uneatlantico.es, roberto.ruiz@uneatlantico.es, silvia.aparicio@uneatlantico.es, jorge.crespo@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2018) Nutritional patterns associated with the maintenance of neurocognitive functions and the risk of dementia and Alzheimer’s disease: A focus on human studies. Pharmacological Research, 131. pp. 32-43. ISSN 10436618