TY  - JOUR
JF  - Food Chemistry
N2  - Traditionally, edible flowers have been used as foods and for therapeutic purposes, today they have gained importance due to their bioactive compounds such as flavonols, anthocyanins or other phenolic compounds, which give them potential for biomedical applications. This work evaluated a methanolic extract of Tulbaghia violacea. Eleven individual phenolic compounds were found and quantified by mass spectrometry in the extract. Antioxidant activity tests (TEAC, FRAP and DPPH) and other characterization parameters were assayed (total phenolic content and total flavonoid content). In vitro studies showed antitumoral activity against ovarian tumoral cells mediated by the induction of non-dependent caspase cell death and by the activation of reactive oxygen species. The effect of the extract against features of Alzheimer disease was in vivo assayed in Caenorhabditis elegans. Tulbaghia extract led to a reduction in the 1?42 beta amyloid peptide formation and prevented oxidative stress. These results suggested that Tulbaghia violacea could be a new source of phenolic compounds for nutraceuticals and functional food development.
Y1  - 2022/07//
VL  - 381
UR  - http://doi.org/10.1016/j.foodchem.2022.132096
SN  - 03088146
ID  - uneatlantico567
TI  - Unravelling potential biomedical applications of the edible flower Tulbaghia violacea
AV  - none
A1  - Rivas-García, Lorenzo
A1  - Romero-Márquez, Jose M.
A1  - Navarro-Hortal, M.D.
A1  - Esteban-Muñoz, Adelaida
A1  - Giampieri, Francesca
A1  - Sumalla Cano, Sandra
A1  - Battino, Maurizio
A1  - Quiles, José L.
A1  - Llopis, Juan
A1  - Sánchez-González, Cristina
KW  - Flower; Quercetin; Autophagy; ROS; Antioxidants; Alzheimer disease
ER  -