@article{uneatlantico48, pages = {379}, volume = {9}, author = {Mar{\'i}a Perales and Pedro L. Valenzuela and Ruben Barakat and Yaiza Cordero and Mireia Pel{\'a}ez and Carmen L{\'o}pez and Luis M. Ruilope and Alejandro Santos-Lozano and Alejandro Lucia}, month = {Enero}, number = {2}, title = {Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up}, journal = {Journal of Clinical Medicine}, year = {2020}, keywords = {Obesity; Hypertension; Diabetes; Pregnancy; Training; Physical activity}, url = {http://repositorio.uneatlantico.es/id/eprint/48/}, abstract = {We studied the influence of pregnancy exercise on maternal/offspring cardiometabolic health until delivery and at follow-up. We pooled data from two randomized controlled trials from our group that were performed following the same methodology (one unpublished). We also collected follow-up data de novo from the participants of both trials and their offspring. In total, 1348 women with uncomplicated, singleton gestations were assigned to an intervention (n = 688, performing a supervised, moderate-intensity exercise program (three sessions/week)) or control group (n = 660). Maternal outcomes were excessive gestational weight gain (EGWG), gestational hypertension/diabetes and, at follow-up, return to pre-pregnancy weight within six months, hypertension, overweight/obesity, and other cardiometabolic conditions. Offspring outcomes were macrosomia and low-birthweight and, at follow-up, overweight/obesity, low-weight, and cardiometabolic conditions. Adherence to the intervention, which proved safe, was {\ensuremath{>}} 95\%. Pregnancy exercise reduced the risk of EGWG, gestational hypertension, and diabetes (adjusted odds ratio (OR) and 95\% confidence interval: 0.60 (0.46?0.79), 0.39 (0.23?0.67), and 0.48 (0.28?0.84)), and it was associated with a greater likelihood of returning to pre-pregnancy weight (2.37 (1.26?4.54)) and a lower risk of maternal cardiometabolic conditions (0.27 (0.08?0.95)) at the end of follow-up (median 6.1 years (interquartile range 1.8)). Pregnancy exercise also reduced the risk of macrosomia (0.36 (0.20?0.63)) and of childhood overweight/obesity during the first year (0.20 (0.06?0.63)). Our findings suggest that pregnancy exercise might protect maternal/offspring health.} }