eprintid: 3588 rev_number: 12 eprint_status: archive userid: 2 dir: disk0/00/00/35/88 datestamp: 2022-09-12 23:30:06 lastmod: 2023-07-17 23:30:29 status_changed: 2022-09-12 23:30:06 type: article metadata_visibility: show creators_name: Liao, Zhiwei creators_name: Zhang, Xuan creators_name: Chen, Xi creators_name: Battino, Maurizio creators_name: Giampieri, Francesca creators_name: Bai, Weibin creators_name: Tian, Lingmin creators_id: creators_id: creators_id: creators_id: maurizio.battino@uneatlantico.es creators_id: francesca.giampieri@uneatlantico.es creators_id: creators_id: title: Recovery of value-added anthocyanins from mulberry by a cation exchange chromatography ispublished: pub subjects: uneat_sn divisions: uneatlantico_produccion_cientifica full_text_status: public keywords: Column chromatography; 001X7; Anthocyanins; Copigments; Isolation; Scale-up abstract: Anthocyanins are often targets in polyphenol analysis. However, it's hard to effectively separate anthocyanin from copigments such as phenolic acid and flavanols due to their similar structure. Thus, a cation exchange chromatography with 001 × 7 has been developed, which is available for anthocyanins isolation both on a small and large scale. The optimal process condition of anthocyanins isolation was determined. Compared to the macroporous adsorbent resins and Strong Cation Exchange resin (SCX), 001X7 shows greater economic advantages in large-scale purification of anthocyanins. More than 95% purity of the anthocyanin fraction can be achieved through this approach. This method shows a path to provide large quantities of copigments-free anthocyanins from mulberry polyphenols for the further study of its biological effects and may be extended to other analytical methods of polyphenol isolation from other plant materials. date: 2022-06 publication: Current Research in Food Science volume: 5 pagerange: 1445-1451 id_number: doi:10.1016/j.crfs.2022.08.022 refereed: TRUE issn: 26659271 official_url: http://doi.org/10.1016/j.crfs.2022.08.022 access: open language: en citation: Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Producción Científica Abierto Inglés Anthocyanins are often targets in polyphenol analysis. However, it's hard to effectively separate anthocyanin from copigments such as phenolic acid and flavanols due to their similar structure. Thus, a cation exchange chromatography with 001 × 7 has been developed, which is available for anthocyanins isolation both on a small and large scale. The optimal process condition of anthocyanins isolation was determined. Compared to the macroporous adsorbent resins and Strong Cation Exchange resin (SCX), 001X7 shows greater economic advantages in large-scale purification of anthocyanins. More than 95% purity of the anthocyanin fraction can be achieved through this approach. This method shows a path to provide large quantities of copigments-free anthocyanins from mulberry polyphenols for the further study of its biological effects and may be extended to other analytical methods of polyphenol isolation from other plant materials. metadata Liao, Zhiwei; Zhang, Xuan; Chen, Xi; Battino, Maurizio; Giampieri, Francesca; Bai, Weibin y Tian, Lingmin mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es, francesca.giampieri@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2022) Recovery of value-added anthocyanins from mulberry by a cation exchange chromatography. Current Research in Food Science, 5. pp. 1445-1451. ISSN 26659271 document_url: http://repositorio.uneatlantico.es/id/eprint/3588/1/1-s2.0-S2665927122001393-main.pdf