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primary topic: https://repositorio.uneatlantico.es/id/eprint/28567

https://repositorio.uneatlantico.es/id/eprint/28567
type: AcademicArticle
type: Article
title: Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation
abstract: Background Physical inactivity and suboptimal diet in pregnancy are important modifiable risk factors for gestational diabetes, a major contributor to pregnancy complications. Objectives We aimed to assess the effects of physical activity and/or diet-based lifestyle interventions during pregnancy on gestational diabetes and if these vary by maternal (body mass index, age, parity, ethnicity, education) and intervention characteristics using individual participant data meta-analysis of randomised trials, and a cost-effectiveness analysis. Data sources International Weight Management in Pregnancy Collaborative Network database was updated by searching major databases from February 2017 to March 2022. Review methods The main outcomes were gestational diabetes by any criteria and by the National Institute for Health and Care Excellence. Other outcomes were gestational diabetes as per International Association of Diabetes in Pregnancy Study Group and maternal and perinatal outcomes. We performed a two-stage random-effects individual participant data meta-analysis to obtain summary estimates (odds ratio) with 95% confidence intervals. Study quality of included trials was assessed, and heterogeneity summarised using τ2. Where possible, we added the aggregate data from non-individual participant data trials to the meta-analysis. We ranked interventions by effectiveness using network meta-analysis and undertook model-based economic evaluation to assess cost-effectiveness. The cost-effectiveness analysis took an NHS cost perspective compared an overall lifestyle intervention versus usual care with a time horizon covering the beginning of pregnancy until the discharge of the mother and infant from the hospital following delivery. Results Ninety-two trials (32,284 women) were included; 54 (23,698 women) provided individual participant data. Lifestyle interventions reduced the odds of gestational diabetes (any criteria) by 10% in individual participant data trials (odds ratio 0.9…
date: 2026-05
is part of: Health Technology Assessment
status: peerReviewed
status: published
author list: authors
creator: Mireia Peláez
type: EPrint
type: ArticleEPrint
is part of: repository
has document: https://repositorio.uneatlantico.es/id/document/1827271
subject: Biomedicine
subject: Physical Education and Sport
subject: Nutrition

https://repositorio.uneatlantico.es/id/document/1827271
type: Document
label: Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation (Texto)
has file: 3051020.pdf
has part: 3051020.pdf

Health Technology Assessment
type: Collection
issn: 20464924

Mahnaz Bahri Khomami
type: Person
given name: Mahnaz Bahri
family name: Khomami

Nuria García de la Torre
type: Person
given name: Nuria García
family name: de la Torre

Frances Austin
type: Person
given name: Frances
family name: Austin

Rachel McNeill
type: Person
given name: Rachel
family name: McNeill

Fabio Facchinetti
type: Person
given name: Fabio
family name: Facchinetti

Gabriel Ruiz Calvo
type: Person
given name: Gabriel Ruiz
family name: Calvo

Christina Vinter
type: Person
given name: Christina
family name: Vinter

Sharon Anne Simpson
type: Person
given name: Sharon Anne
family name: Simpson

Elisabetta Petrella
type: Person
given name: Elisabetta
family name: Petrella

Nicola Heslehurst
type: Person
given name: Nicola
family name: Heslehurst

Richard D Riley
type: Person
given name: Richard D
family name: Riley

Jose Guilherme Cecatti
type: Person
given name: Jose Guilherme
family name: Cecatti

Ana Pilar Betrán
type: Person
given name: Ana Pilar
family name: Betrán

Alka Kothari
type: Person
given name: Alka
family name: Kothari

Javier Zamora
type: Person
given name: Javier
family name: Zamora

Krish Nirantharakumar
type: Person
given name: Krish
family name: Nirantharakumar

Ghadir Mahmoud
type: Person
given name: Ghadir
family name: Mahmoud

Tarja I Kinnunen
type: Person
given name: Tarja I
family name: Kinnunen

Chidubem Okeke Ogwulu
type: Person
given name: Chidubem Okeke
family name: Ogwulu

Kelly C Allison
type: Person
given name: Kelly C
family name: Allison

Stamatina Iliodromiti
type: Person
given name: Stamatina
family name: Iliodromiti

Mark Monahan
type: Person
given name: Mark
family name: Monahan

Shakila Thangaratinam
type: Person
given name: Shakila
family name: Thangaratinam

Fionnuala M McAuliffe
type: Person
given name: Fionnuala M
family name: McAuliffe

Tracy Roberts
type: Person
given name: Tracy
family name: Roberts

Dyuti Coomar
type: Person
given name: Dyuti
family name: Coomar

John Allotey
type: Person
given name: John
family name: Allotey

Jonatan R Ruiz
type: Person
given name: Jonatan R
family name: Ruiz

Graham A Hitman
type: Person
given name: Graham A
family name: Hitman

Valencia Kabeya
type: Person
given name: Valencia
family name: Kabeya

Kristina Martha Renault
type: Person
given name: Kristina Martha
family name: Renault

Annick Bogaerts
type: Person
given name: Annick
family name: Bogaerts

Dorte Møller Jensen
type: Person
given name: Dorte Møller
family name: Jensen

Joie Ensor
type: Person
given name: Joie
family name: Ensor

Garry Shen
type: Person
given name: Garry
family name: Shen

Lucilla Poston
type: Person
given name: Lucilla
family name: Poston

Suzanne Phelan
type: Person
given name: Suzanne
family name: Phelan

Anna Boath
type: Person
given name: Anna
family name: Boath

Alfonso Luis Calle Pascual
type: Person
given name: Alfonso Luis Calle
family name: Pascual

Narges Sadat Motahari-Tabari
type: Person
given name: Narges Sadat
family name: Motahari-Tabari

Julie Dodds
type: Person
given name: Julie
family name: Dodds

Cheryce Harrison
type: Person
given name: Cheryce
family name: Harrison

Helena Teede
type: Person
given name: Helena
family name: Teede

Mireia Peláez
type: Person
given name: Mireia
family name: Peláez

Ngawai Moss
type: Person
given name: Ngawai
family name: Moss

http://repositorio.uneatlantico.es/id/eprint/28567/
title: HTML Summary of #28567 Effects of physical activity and diet in pregnancy to prevent gestational diabetes: an individual participant data (IPD) meta-analysis on the differential effects of interventions with economic evaluation
format: text/html
primary topic: https://repositorio.uneatlantico.es/id/eprint/28567

Biomedicine
type: Concept
preferred label: Biomedicina @es

Physical Education and Sport
type: Concept
preferred label: Educación física y el deporte @es

Nutrition
type: Concept
preferred label: Alimentación @es