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primary topic: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials

The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials
type: AcademicArticle
type: Article
abstract: The rising prevalence of cognitive disorders highlights the urgent need for effective prevention strategies and therapeutic interventions. While adherence to a balanced diet has been associated with a reduced risk of cognitive decline, emerging evidence underscores the potential role of plant-derived bioactive compounds, such as (poly)phenols, with anthocyanins receiving increasing attention. This meta-analysis aimed to evaluate the effect of anthocyanin-rich interventions on cognitive performance. A systematic search of randomized controlled trials (RCTs) assessing the effects of anthocyanin supplementation and cognitive outcomes identified 59 eligible studies. Overall, anthocyanin intervention significantly improved global cognition (standardized mean difference (SMD) = 0.46, 95% CI = 0.30 to 0.63, I2 = 0.0%) compared with controls. Domain-specific analyses further revealed significant benefits for visuospatial processing/reasoning and attention (SMD = 0.37, 95% CI = 0.18 to 0.55, I2 = 76.3%), processing and psychomotor speed (SMD = 0.19, 95% CI = 0.05 to 0.34, I2 = 64.0%), verbal speed and fluency (SMD = 0.21, 95% CI = 0.03 to 0.39, I2 = 30.5%), episodic memory (SMD = 0.30, 95% CI = 0.10 to 0.50, I2 = 75.9%), and working memory (SMD = 0.24, 95% CI = 0.12 to 0.36, I2 = 46.5%). Collectively, these findings suggest that anthocyanin supplementation may improve multiple cognitive domains. Although these results are promising, further well-designed RCTs are needed to validate these outcomes and consolidate the current evidence base.
date: 2025-12
is part of: GeroScience
status: peerReviewed
status: published
author list: authors
type: EPrint
type: ArticleEPrint
is part of: repository
has document: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Texto)
has document: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Otro)
subject: Nutrition

The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Texto)
type: Document
has file: s11357-025-02008-7.pdf
has part: s11357-025-02008-7.pdf

GeroScience
type: Collection
issn: 25092723

José L. Quiles
type: Person
given name: José L.
family name: Quiles

Giuseppe Grosso
type: Person
given name: Giuseppe
family name: Grosso

Nicola Veronese
type: Person
given name: Nicola
family name: Veronese

Agnieszka Micek
type: Person
given name: Agnieszka
family name: Micek

Evelyn Frias-Toral
type: Person
given name: Evelyn
family name: Frias-Toral

Maurizio Battino
type: Person
given name: Maurizio
family name: Battino

Francesca Giampieri
type: Person
given name: Francesca
family name: Giampieri

Mario Siervo
type: Person
given name: Mario
family name: Siervo

Pedro Mena
type: Person
given name: Pedro
family name: Mena

Justyna Godos
type: Person
given name: Justyna
family name: Godos

Fabio Galvano
type: Person
given name: Fabio
family name: Galvano

Giuseppe Caruso
type: Person
given name: Giuseppe
family name: Caruso

Jianbo Xiao
type: Person
given name: Jianbo
family name: Xiao

Zoltan Ungvari
type: Person
given name: Zoltan
family name: Ungvari

David Vauzour
type: Person
given name: David
family name: Vauzour

Daniele Del Rio
type: Person
given name: Daniele
family name: Del Rio

Irma Domínguez Azpíroz
type: Person
given name: Irma Domínguez
family name: Azpíroz

The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Otro)
type: Document
is version of: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Texto)
is volatile version of: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Texto)
is index codes version of: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials (Texto)
has file: indexcodes.txt
has part: indexcodes.txt

HTML Summary of #17891 The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials
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primary topic: The effect of anthocyanins and anthocyanin-rich foods on cognitive function: a meta-analysis of randomized controlled trials

Nutrition
type: Concept
preferred label: Alimentación @es