eprintid: 17594 rev_number: 8 eprint_status: archive userid: 2 dir: disk0/00/01/75/94 datestamp: 2025-04-10 23:30:11 lastmod: 2025-04-10 23:30:13 status_changed: 2025-04-10 23:30:11 type: article metadata_visibility: show creators_name: Martín-Rodríguez, Francisco creators_name: Martín-Sánchez, Rafael creators_name: del Pozo Vegas, Carlos creators_name: Lopez-Izquierdo, Raúl creators_name: Martín-Conty, José Luis creators_name: Silva Alvarado, Eduardo René creators_name: Gracia Villar, Santos creators_name: Dzul López, Luis Alonso creators_name: Aparicio Obregón, Silvia creators_name: Calderón Iglesias, Rubén creators_name: Sanz-García, Ancor creators_name: Castro Villamor, Miguel Ángel creators_id: creators_id: creators_id: creators_id: creators_id: creators_id: eduardo.silva@funiber.org creators_id: santos.gracia@uneatlantico.es creators_id: luis.dzul@uneatlantico.es creators_id: silvia.aparicio@uneatlantico.es creators_id: ruben.calderon@uneatlantico.es creators_id: creators_id: title: Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation ispublished: pub subjects: uneat_bm divisions: uneatlantico_produccion_cientifica divisions: unincol_produccion_cientifica divisions: uninimx_produccion_cientifica divisions: uninipr_produccion_cientifica divisions: unic_produccion_cientifica divisions: uniromana_produccion_cientifica full_text_status: public keywords: Anxiety, High-fidelity clinical simulation, STAI, Pupillary diameter, Learning abstract: The aim of the present work was to determine the correlation between the State-Trait Anxiety Inventory (STAI) score and pupillary diameter and whether this correlation exists to develop a predictive model of anxiety with the pupillary diameter of students exposed to high-fidelity clinical simulation. This was a randomized, blinded, simulation-based clinical trial. The study was conducted at the Advanced Clinical Simulation Center, Faculty of Medicine, Valladolid University (Spain), from February 1 to April 15, 2023, and involved volunteer sixth-year undergraduate medical students. The STAI score, vital signs (oxygen saturation, perfusion index, blood pressure, heart rate, and temperature), and pupillary response were assessed. The primary outcomes were the delta (pre/postsimulation) of the state STAI and the delta of the pupillary diameter. Sixty-one sixth-year students fulfilled the inclusion criteria. There was no difference regarding the clinical scenario. There was a statistically significant correlation between the state STAI score and pupillary diameter. The predictive model had an AUC of 0.876, with the delta diameter of the pupillary being the only statistically significant variable for anxiety prediction. Our results showed that both the pupillary response and the STAI score allowed the identification of students with disabling anxiety. These results could pave the way for appropriate protocol development that allows for personalized tutoring of students with elevated anxiety levels. date: 2025-03 publication: Scientific Reports volume: 15 number: 1 id_number: doi:10.1038/s41598-025-95290-6 refereed: TRUE issn: 2045-2322 official_url: http://doi.org/10.1038/s41598-025-95290-6 access: open language: en citation: Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Artículos y libros Fundación Universitaria Internacional de Colombia > Investigación > Producción Científica Universidad Internacional Iberoamericana México > Investigación > Producción Científica Universidad Internacional Iberoamericana Puerto Rico > Investigación > Producción Científica Universidad Internacional do Cuanza > Investigación > Producción Científica Universidad de La Romana > Investigación > Producción Científica Abierto Inglés The aim of the present work was to determine the correlation between the State-Trait Anxiety Inventory (STAI) score and pupillary diameter and whether this correlation exists to develop a predictive model of anxiety with the pupillary diameter of students exposed to high-fidelity clinical simulation. This was a randomized, blinded, simulation-based clinical trial. The study was conducted at the Advanced Clinical Simulation Center, Faculty of Medicine, Valladolid University (Spain), from February 1 to April 15, 2023, and involved volunteer sixth-year undergraduate medical students. The STAI score, vital signs (oxygen saturation, perfusion index, blood pressure, heart rate, and temperature), and pupillary response were assessed. The primary outcomes were the delta (pre/postsimulation) of the state STAI and the delta of the pupillary diameter. Sixty-one sixth-year students fulfilled the inclusion criteria. There was no difference regarding the clinical scenario. There was a statistically significant correlation between the state STAI score and pupillary diameter. The predictive model had an AUC of 0.876, with the delta diameter of the pupillary being the only statistically significant variable for anxiety prediction. Our results showed that both the pupillary response and the STAI score allowed the identification of students with disabling anxiety. These results could pave the way for appropriate protocol development that allows for personalized tutoring of students with elevated anxiety levels. metadata Martín-Rodríguez, Francisco; Martín-Sánchez, Rafael; del Pozo Vegas, Carlos; Lopez-Izquierdo, Raúl; Martín-Conty, José Luis; Silva Alvarado, Eduardo René; Gracia Villar, Santos; Dzul López, Luis Alonso; Aparicio Obregón, Silvia; Calderón Iglesias, Rubén; Sanz-García, Ancor y Castro Villamor, Miguel Ángel mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, eduardo.silva@funiber.org, santos.gracia@uneatlantico.es, luis.dzul@uneatlantico.es, silvia.aparicio@uneatlantico.es, ruben.calderon@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Pupilometer efficacy in monitoring anxiety in undergraduate medical students during high-fidelity clinical simulation. Scientific Reports, 15 (1). ISSN 2045-2322 document_url: http://repositorio.uneatlantico.es/id/eprint/17594/1/s41598-025-95290-6.pdf