TY  - JOUR
N2  - Background:
Flavonoids are naturally occurring dietary phytochemicals with significant antioxidant effects aside from several health benefits. People often consume them in combination with other food components. Compiling data establishes a link between bioactive flavonoids and prevention of several diseases in animal models, including cardiovascular diseases, diabetes, gut dysbiosis, and metabolic dysfunction-associated steatotic liver disease (MASLD). However, numerous clinical studies have demonstrated the ineffectiveness of flavonoids contradicting rodent models, thereby challenging the validity of using flavonoids as dietary supplements.
Aim of Review:
This review provides a clinical perspective to emphasize the effective roles of dietary flavonoids as well as to summarize their specific mechanisms in animals briefly.
AV  - public
KW  - Dietary flavonoids; Metabolism; Metabolic disorder; Health benefits;Clinical evidence
SN  - 20901232
JF  - Journal of Advanced Research
ID  - uneatlantico16153
TI  - Flavonoids for gastrointestinal tract local and associated systemic effects: A review of clinical trials and future perspectives
Y1  - 2025/01//
UR  - http://doi.org/10.1016/j.jare.2025.01.014
A1  - Li, Xiaopeng
A1  - Xie, Enjun
A1  - Sun, Shumin
A1  - Shen, Jie
A1  - Ding, Yujin
A1  - Wang, Jiaqi
A1  - Peng, Xiaoyu
A1  - Zheng, Ruting
A1  - Farag, Mohamed A.
A1  - Xiao, Jianbo
ER  -