relation: http://repositorio.uneatlantico.es/id/eprint/15982/ canonical: http://repositorio.uneatlantico.es/id/eprint/15982/ title: Enzymatic treatment shapes in vitro digestion pattern of phenolic compounds in mulberry juice creator: Luo, Peihuan creator: Ai, Jian creator: Wang, Qiongyao creator: Lou, Yihang creator: Liao, Zhiwei creator: Giampieri, Francesca creator: Battino, Maurizio creator: Sieniawska, Elwira creator: Bai, Weibin creator: Tian, Lingmin subject: Alimentación description: The health benefits of mulberry fruit are closely associated with its phenolic compounds. However, the effects of enzymatic treatments on the digestion patterns of these compounds in mulberry juice remain largely unknown. This study investigated the impact of pectinase (PE), pectin lyase (PL), and cellulase (CE) on the release of phenolic compounds in whole mulberry juice. The digestion patterns were further evaluated using an in vitro simulated digestion model. The results revealed that PE significantly increased chlorogenic acid content by 77.8 %, PL enhanced cyanidin-3-O-glucoside by 20.5 %, and CE boosted quercetin by 44.5 %. Following in vitro digestion, the phenolic compound levels decreased differently depending on the treatment, while cyanidin-3-O-rutinoside content increased across all groups. In conclusion, the selected enzymes effectively promoted the release of phenolic compounds in mulberry juice. However, during gastrointestinal digestion, the degradation of phenolic compounds surpassed their enhanced release, with effects varying based on the compound's structure. date: 2025-12 type: Artículo type: PeerReviewed identifier: Artículo Materias > Alimentación Universidad Europea del Atlántico > Investigación > Artículos y libros Cerrado Inglés The health benefits of mulberry fruit are closely associated with its phenolic compounds. However, the effects of enzymatic treatments on the digestion patterns of these compounds in mulberry juice remain largely unknown. This study investigated the impact of pectinase (PE), pectin lyase (PL), and cellulase (CE) on the release of phenolic compounds in whole mulberry juice. The digestion patterns were further evaluated using an in vitro simulated digestion model. The results revealed that PE significantly increased chlorogenic acid content by 77.8 %, PL enhanced cyanidin-3-O-glucoside by 20.5 %, and CE boosted quercetin by 44.5 %. Following in vitro digestion, the phenolic compound levels decreased differently depending on the treatment, while cyanidin-3-O-rutinoside content increased across all groups. In conclusion, the selected enzymes effectively promoted the release of phenolic compounds in mulberry juice. However, during gastrointestinal digestion, the degradation of phenolic compounds surpassed their enhanced release, with effects varying based on the compound's structure. metadata Luo, Peihuan; Ai, Jian; Wang, Qiongyao; Lou, Yihang; Liao, Zhiwei; Giampieri, Francesca; Battino, Maurizio; Sieniawska, Elwira; Bai, Weibin y Tian, Lingmin mail SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, francesca.giampieri@uneatlantico.es, maurizio.battino@uneatlantico.es, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR (2025) Enzymatic treatment shapes in vitro digestion pattern of phenolic compounds in mulberry juice. Food Chemistry, 469. p. 142555. ISSN 03088146 relation: http://doi.org/10.1016/j.foodchem.2024.142555 relation: doi:10.1016/j.foodchem.2024.142555 language: en