eprintid: 149 rev_number: 11 eprint_status: archive userid: 2 importid: 0 dir: disk0/00/00/01/49 datestamp: 2021-06-01 23:55:15 lastmod: 2022-03-03 23:55:10 status_changed: 2021-06-01 23:55:15 type: article succeeds: 0 commentary: 0 metadata_visibility: show item_issues_count: 0 sword_depositor: 0 creators_name: Giampieri, Francesca creators_name: Forbes-Hernandez, Tamara Y. creators_name: Gasparrini, Massimiliano creators_name: Alvarez-Suarez, José M. creators_name: Afrin, Sadia creators_name: Bompadre, Stefano creators_name: Quiles, José L. creators_name: Mezzetti, Bruno creators_name: Battino, Maurizio creators_id: creators_id: tamara.forbes@unini.edu.mx creators_id: creators_id: creators_id: creators_id: creators_id: creators_id: creators_id: maurizio.battino@uneatlantico.es title: Strawberry as a health promoter: an evidence based review ispublished: pub subjects: uneat_bm divisions: uneatlantico_produccion_cientifica full_text_status: none keywords: Strawberry, Polyphenols, Inflammation, Cardiovascular diseases, Cancer, Neurodegenerative diseases. abstract: Since a high intake of fruits and vegetables is inversely related to the incidence of several degenerative diseases, the importance of a balanced diet in relation to human health has received increased consumer attention worldwide. Strawberries (Fragaria X ananassa, Duch.) are a rich source of a wide variety of nutritive compounds such as sugars, vitamins, and minerals, as well as non-nutritive, bioactive compounds such as flavonoids, anthocyanins and phenolic acids. All of these compounds exert a synergistic and cumulative effect on human health promotion and in disease prevention. Strawberry phenolics are indeed able (i) to detoxify free radicals blocking their production, (ii) to modulate the expression of genes involved in metabolism, cell survival and proliferation and antioxidant defense, and (iii) to protect and repair DNA damage. The overall objective of the present review is to update and discuss the key findings, from recent in vivo studies, on the effects of strawberries on human health. Particular attention will be paid to the molecular mechanisms proposed to explain the health effects of polyphenols against the most common diseases related to oxidative stress driven pathologies, such as cancer, cardiovascular diseases, type II diabetes, obesity and neurodegenerative diseases, and inflammation. date: 2015 date_type: published publication: Food & Function volume: 6 number: 5 pagerange: 1386-1398 pages: 0 id_number: doi:10.1039/c5fo00147a refereed: TRUE issn: 2042-6496 official_url: http://doi.org/10.1039/c5fo00147a num_pieces: 0 gscholar_impact: 0 gscholar_datestamp: 0000-00-00 00:00:00 access: close language: en citation: Artículo Materias > Biomedicina Universidad Europea del Atlántico > Investigación > Producción Científica Cerrado Inglés Since a high intake of fruits and vegetables is inversely related to the incidence of several degenerative diseases, the importance of a balanced diet in relation to human health has received increased consumer attention worldwide. Strawberries (Fragaria X ananassa, Duch.) are a rich source of a wide variety of nutritive compounds such as sugars, vitamins, and minerals, as well as non-nutritive, bioactive compounds such as flavonoids, anthocyanins and phenolic acids. All of these compounds exert a synergistic and cumulative effect on human health promotion and in disease prevention. Strawberry phenolics are indeed able (i) to detoxify free radicals blocking their production, (ii) to modulate the expression of genes involved in metabolism, cell survival and proliferation and antioxidant defense, and (iii) to protect and repair DNA damage. The overall objective of the present review is to update and discuss the key findings, from recent in vivo studies, on the effects of strawberries on human health. Particular attention will be paid to the molecular mechanisms proposed to explain the health effects of polyphenols against the most common diseases related to oxidative stress driven pathologies, such as cancer, cardiovascular diseases, type II diabetes, obesity and neurodegenerative diseases, and inflammation. metadata Giampieri, Francesca; Forbes-Hernandez, Tamara Y.; Gasparrini, Massimiliano; Alvarez-Suarez, José M.; Afrin, Sadia; Bompadre, Stefano; Quiles, José L.; Mezzetti, Bruno y Battino, Maurizio mail SIN ESPECIFICAR, tamara.forbes@unini.edu.mx, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, SIN ESPECIFICAR, maurizio.battino@uneatlantico.es (2015) Strawberry as a health promoter: an evidence based review. Food & Function, 6 (5). pp. 1386-1398. ISSN 2042-6496