%A Alexandre Díaz-Pons
%A Marina Soler-Andrés
%A Víctor Ortiz-García de la Foz
%A Nancy Murillo-García
%A Angel Yorca-Ruiz
%A Rebeca Magdaleno Herrero
%A Sergio Castaño-Castaño
%A Alexandre González-Rodríguez
%A Esther Setién-Suero
%A Rosa Ayesa-Arriola
%X Purpose
The study aimed to explore the role of parenthood at first episode of psychosis (FEP) on recovery, with a focus on potential sex differences.

Methods
Sociodemographic, clinical, and neurocognitive information was considered on 610 FEP patients form the PAFIP cohort (Spain). Baseline and three-year follow-up comparisons were carried out. Chi-square tests and ANCOVA analysis were performed controlling for the effect of age and years of education.

Results
Men comprised 57.54% of the sample, with only 5.41% having offspring when compared to 36.29% of women. Parenthood was related to shorter duration of untreated illness (DUI) in women with children (12.08 months mothers vs. 27.61 months no mothers), showing mothers better premorbid adjustment as well. Childless men presented the worst premorbid adjustment and the highest cannabis and tobacco consumption rates. Mothers presented better global cognitive function, particularly in attention, motor dexterity and executive function at three-year follow-up.

Conclusions
Diminished parental rates among FEP men could be suggested as a consequence of a younger age of illness onset. Sex roles in caregiving may explain the potential role of parenthood on premorbid phase, with a better and heathier profile, and a more favorable long-term outcome in women. These characteristics may be relevant when adjusting treatment specific needs in men and women with and without offspring.
%L uneatlantico12500
%J Archives of Women's Mental Health
%D 2024
%R doi:10.1007/s00737-024-01457-x
%K First episode of psychosis; Offspring; Neuropsychology; Sex-differences; Women
%T Exploring parenthood in first episode of psychosis: the potential role of the offspring in the outcome of women