TY - JOUR ID - uneatlantico12500 TI - Exploring parenthood in first episode of psychosis: the potential role of the offspring in the outcome of women N2 - Purpose The study aimed to explore the role of parenthood at first episode of psychosis (FEP) on recovery, with a focus on potential sex differences. Methods Sociodemographic, clinical, and neurocognitive information was considered on 610 FEP patients form the PAFIP cohort (Spain). Baseline and three-year follow-up comparisons were carried out. Chi-square tests and ANCOVA analysis were performed controlling for the effect of age and years of education. Results Men comprised 57.54% of the sample, with only 5.41% having offspring when compared to 36.29% of women. Parenthood was related to shorter duration of untreated illness (DUI) in women with children (12.08 months mothers vs. 27.61 months no mothers), showing mothers better premorbid adjustment as well. Childless men presented the worst premorbid adjustment and the highest cannabis and tobacco consumption rates. Mothers presented better global cognitive function, particularly in attention, motor dexterity and executive function at three-year follow-up. Conclusions Diminished parental rates among FEP men could be suggested as a consequence of a younger age of illness onset. Sex roles in caregiving may explain the potential role of parenthood on premorbid phase, with a better and heathier profile, and a more favorable long-term outcome in women. These characteristics may be relevant when adjusting treatment specific needs in men and women with and without offspring. A1 - Díaz-Pons, Alexandre A1 - Soler-Andrés, Marina A1 - Ortiz-García de la Foz, Víctor A1 - Murillo-García, Nancy A1 - Yorca-Ruiz, Angel A1 - Magdaleno Herrero, Rebeca A1 - Castaño-Castaño, Sergio A1 - González-Rodríguez, Alexandre A1 - Setién-Suero, Esther A1 - Ayesa-Arriola, Rosa AV - none JF - Archives of Women's Mental Health KW - First episode of psychosis; Offspring; Neuropsychology; Sex-differences; Women Y1 - 2024/03// UR - http://doi.org/10.1007/s00737-024-01457-x SN - 1434-1816 ER -