TY  - JOUR
N2  - The aim of this work is to develop different encapsulated propolis ingredients by spray-drying and to evaluate their bioaccessibility using simulated in vitro digestion. To achieve these goals, first, microparticles of a propolis extract with inulin as the coating polymer were prepared under the optimal conditions previously determined. Then, a fraction of inulin was replaced with other encapsulating agents, namely sodium alginate, pectin, and chitosan, to obtain different ingredients with controlled release properties in the gastrointestinal tract. The analysis of the phenolic profile in the propolis extract and microparticles showed 58 compounds tentatively identified, belonging mainly to phenolic acid derivatives and flavonoids. Then, the behavior of the free extract and the formulated microparticles under gastrointestinal conditions was studied through an in vitro gastrointestinal digestion process using the INFOGEST protocol. Digestion of the free extract resulted in the degradation of most compounds, which was minimized in the encapsulated formulations. Thus, all developed microparticles could be promising strategies for improving the stability of this bioactive extract under gastrointestinal conditions, thereby enhancing its beneficial effect.
Y1  - 2024/01//
TI  - Influence of the Encapsulating Agent on the Bioaccessibility of Phenolic Compounds from Microencapsulated Propolis Extract during "In Vitro" Gastrointestinal Digestion
KW  - propolis; encapsulation; spray-drying; bioaccessibility; in vitro gastrointestinal digestion; HPLC-ESI-QTOF-MS/MS
IS  - 3
UR  - http://doi.org/10.3390/foods13030425
A1  - Cea-Pavez, Inés
A1  - Manteca-Bautista, David
A1  - Morillo-Gomar, Alejandro
A1  - Quirantes-Piné, Rosa
A1  - Quiles, José L.
SN  - 2304-8158
AV  - public
ID  - uneatlantico11260
VL  - 13
JF  - Foods
ER  -